Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 5/20 | 0.35 |
| ▸ | CTSS | P25774 | 5/20 | 0.35 |
| ▸ | CTSK | P43235 | 3/20 | 0.35 |
| ▸ | CTSL | P07711 | 4/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5366950 | 0.85 | CTSB (0.46) | ALDH1A1CTSBCTSSCTSKCTSL | |
| SCHEMBL5360282 | 0.80 | TSHR (0.41) | ALDH1A1CTSBCTSSCTSKCTSL | |
| SCHEMBL5360348 | 0.80 | CTSB (0.41) | ALDH1A1CTSBCTSSCTSKCTSL | |
| SCHEMBL5363933 | 0.79 | USP2 (0.41) | ALDH1A1CTSBCTSSCTSKCTSL | |
| SCHEMBL5374907 | 0.79 | TSHR (0.47) | ALDH1A1CTSSCTSL | |
| SCHEMBL5367124 | 0.79 | ALDH1A1 (0.46) | ALDH1A1CTSBCTSSCTSKCTSL | |
| SCHEMBL5364788 | 0.78 | SMN1; SMN2 (0.51) | ALDH1A1CTSS | |
| SCHEMBL5364807 | 0.78 | CTSS (0.47) | ALDH1A1CTSSCTSL | |
| SCHEMBL7074638 | 0.78 | OPRM1 (0.34) | ALDH1A1POLBGAACTSBCTSS | |
| SCHEMBL5366879 | 0.77 | CTSL (0.36) | ALDH1A1CTSBCTSSCTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030225270-A1 | Compounds useful as reversible inhibitors of cysteine proteases | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2003-12-04 | — | — | US | disclosed |
| US-20030225271-A1 | Compounds useful as reversible inhibitors of cysteine proteases | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2003-12-04 | — | — | US | disclosed |
| US-20020058809-A1 | Compounds useful as reversible inhibitors of cysteine proteases | EMMANUEL MICHEL JOSE (US) | 2002-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020058809-A1 | Compounds useful as reversible inhibitors of cysteine proteases | CTSS, CTSK, CTSB | ALDH1A1 1811/4885POLB 1418/4885GAA 176/4885 |
| US-20030225270-A1 | Compounds useful as reversible inhibitors of cysteine proteases | CTSS, CTSK, CTSB | ALDH1A1 1811/4885POLB 1418/4885GAA 176/4885 |
| US-20030225271-A1 | Compounds useful as reversible inhibitors of cysteine proteases | CTSS, CTSK, CTSB | ALDH1A1 1811/4885POLB 1418/4885GAA 176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.