SCHEMBL707230

SCHEMBL707230

CS(=O)(=O)O[C@H]1CCOC1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LRRK2 Q5S007 2/20 0.31
GPR119 Q8TDV5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL709288 1.00 LRRK2 (0.31) LRRK2GPR119
SCHEMBL707231 1.00 LRRK2 (0.31) LRRK2GPR119
SCHEMBL3826761 0.91 GPR119 (0.31) GPR119
SCHEMBL28756731 0.88 CA1 (0.33)
SCHEMBL707215 0.88 CA1 (0.33)
SCHEMBL224278 0.86 CA1 (0.33)
SCHEMBL9562903 0.81
SCHEMBL28718773 0.81
SCHEMBL28363128 0.79 PDE4D (0.33)
SCHEMBL26699713 0.79 CA1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 246 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260138986-A1 PYRROLOTRIAZINE DERIVATIVES FOR TREATING KIT- AND PDGFRA-MEDIATED DISEASES BLUEPRINT MEDICINES CORP (US) 2026-05-21 US disclosed
US-12552786-B2 Inhibitors of αvβ6 integrin MORPHIC THERAPEUTIC, INC. (US) 2026-02-17 US disclosed
EP-4692076-A1 HIV INHIBITOR COMPOUNDS Gilead Sciences, Inc. (US) 2026-02-11 EP disclosed
US-12514859-B2 Pyrazole pyrimidine derivative and uses thereof YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) 2026-01-06 US disclosed
US-12479853-B2 HIV inhibitor compounds GILEAD SCIENCES, INC. (US) 2025-11-25 US disclosed
EP-3909949-B1 ATAZANAVIR (ATV) ANALOGUES FOR TREATING HIV INFECTIONS GILEAD SCIENCES INC (US) 2025-10-15 EP disclosed
EP-4574210-A2 KAPPA OPIOID RECEPTOR ANTAGONISTS AND PRODUCTS AND METHODS RELATED THERETO The Scripps Research Institute (US) 2025-06-25 EP disclosed
EP-4539840-A1 KINASE MODULATORS AND METHODS OF USE THEREOF Neuron23, Inc. (US) 2025-04-23 EP disclosed
EP-4267574-B1 6-HETEROARYLOXY BENZIMIDAZOLES AND AZABENZIMIDAZOLES AS JAK2 INHIBITORS AJAX THERAPEUTICS INC (US) 2025-04-23 EP disclosed
US-20250115597-A1 TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF LYNK PHARMACEUTICALS CO LTD (CN) 2025-04-10 US disclosed
US-7488745-B2 Compounds for the treatment of inflammatory disorders SCHERING CORPORATION (US) 2009-02-10 US disclosed
US-7488745-B2 Compounds for the treatment of inflammatory disorders SCHERING CORPORATION (US) 2009-02-10 US disclosed
US-20070219218-A1 Compounds for the treatment of inflammatory disorders SCHERING CORPORATION 2007-09-20 US disclosed
US-20070219218-A1 Compounds for the treatment of inflammatory disorders SCHERING CORPORATION 2007-09-20 US disclosed
WO-2007084415-A2 COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS SCHERING CORPORATION (US) 2007-07-26 WO disclosed
EP-1244645-B1 STEREOSPECIFIC HYDROLYSIS OF OPTICALLY ACTIVE ESTERS SIGMA TAU IND FARMACEUTI (IT) 2004-08-25 EP disclosed
US-6593478-B2 Preparing carnitine SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) 2003-07-15 US disclosed
US-20030032818-A1 Reacting a sulfonic, phosphoric, or phosphonic acid with an aqueous strong organic or inorganic acid at 60-100 degrees c SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) 2003-02-13 US disclosed
EP-1244645-A1 STEREOSPECIFIC HYDROLYSIS OF OPTICALLY ACTIVE ESTERS Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) 2002-10-02 EP disclosed
WO-2001047908-A1 STEREOSPECIFIC HYDROLYSIS OF OPTICALLY ACTIVE ESTERS SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) 2001-07-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070219218-A1 Compounds for the treatment of inflammatory disorders ADAMTS1, ADAMTS13, ADAMTS7 LRRK2 3562/4885GPR119 1823/4885
US-12552786-B2 Inhibitors of αvβ6 integrin ITGB6, ITGB1, ITGA6 LRRK2 1696/4885GPR119 1650/4885
US-20030032818-A1 Reacting a sulfonic, phosphoric, or phosphonic acid with an aqueous strong organic or inorganic acid at 60-100 degrees c CPT1B, CPT1A, SLC25A20 LRRK2 4816/4885GPR119 201/4885
US-12479853-B2 HIV inhibitor compounds NFATC1, SAMHD1, CCR5 LRRK2 1100/4885GPR119 2624/4885
US-20250115597-A1 TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF TYK2, JAK2, JAK1 LRRK2 132/4885GPR119 1654/4885
US-20260138986-A1 PYRROLOTRIAZINE DERIVATIVES FOR TREATING KIT- AND PDGFRA-MEDIATED DISEASES KIT, PDGFRA, PDGFRB LRRK2 278/4885GPR119 548/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.