SCHEMBL7072379

SCHEMBL7072379

c1ccc(Cc2ccc3cn[nH]c3c2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 4/20 0.57
CDK2 P24941 3/20 0.50
HSP90AA1 P07900 1/20 0.50
IDO1 P14902 1/20 0.50
MKNK1 Q9BUB5 1/20 0.49
MKNK2 Q9HBH9 1/20 0.49
DYRK1A Q13627 5/20 0.49
NOS1 P29475 2/20 0.49
KDM4E B2RXH2 2/20 0.49
MAPT P10636 2/20 0.49
METAP2 P50579 2/20 0.49
MEN1 O00255 1/20 0.49
PKM P14618 1/20 0.49
HTT P42858 1/20 0.49
KMT2A Q03164 1/20 0.49
GSK3B P49841 3/20 0.47
CDK5 Q00535 3/20 0.47
AURKA O14965 2/20 0.47
DAPK3 O43293 2/20 0.47
JAK2 O60674 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14196189 0.86 GSK3B (0.57) FGFR1CDK2HSP90AA1IDO1MKNK2
SCHEMBL28047882 0.84 MKNK1 (0.55) FGFR1MKNK1MKNK2DYRK1ANOS1
SCHEMBL28253335 0.84 FGFR1 (0.57) FGFR1CDK2DYRK1ANOS1KDM4E
SCHEMBL8669605 0.80 NOS1 (0.57) FGFR1CDK2HSP90AA1IDO1DYRK1A
SCHEMBL8713967 0.78 FGFR1 (0.51) FGFR1CDK2HSP90AA1IDO1MKNK1
SCHEMBL23023034 0.77 GAA (0.50) FGFR1MKNK1MKNK2KDM4EMAPT
SCHEMBL879376 0.77 NOS1 (0.53) FGFR1CDK2HSP90AA1IDO1DYRK1A
SCHEMBL30896276 0.77 NOS1 (0.58) FGFR1CDK2HSP90AA1IDO1DYRK1A
SCHEMBL20721589 0.77 MAPT (0.53) FGFR1CDK2HSP90AA1IDO1DYRK1A
SCHEMBL91332 0.77 MAPT (0.60) FGFR1CDK2HSP90AA1IDO1DYRK1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4925901-A STORAGE STAABILITY, ONIUM ION CATALYST THE DOW CHEMICAL COMPANY (US) 1990-05-15 US claimed
EP-3265447-B1 BENZOXAZINE LOW TEMPERATURE CURABLE COMPOSITION HUNTSMAN ADVANCED MAT AMERICAS LLC (US) 2023-03-01 EP disclosed
CN-107428708-B Benzoxazine low temperature curable compositions 亨斯迈先进材料美国有限责任公司 2021-11-09 CN disclosed
US-20180030264-A1 Benzoxazine Low Temperature Curable Composition HUNTSMAN ADVANCED MATERIALS AMERICAS LLC 2018-02-01 US disclosed
EP-3265447-A1 BENZOXAZINE LOW TEMPERATURE CURABLE COMPOSITION Huntsman Advanced Materials Americas LLC (US) 2018-01-10 EP disclosed
EP-0458502-B1 Latent catalysts, cure-inhibited epoxy resin compositions and laminates prepared therefrom DOW GLOBAL TECHNOLOGIES INC (US) 2003-06-18 EP disclosed
CN-1050617-C Latent catalysts, cure-inhibited epxoy resin compositions and laminates prepared therefrom DOW CHEMICAL CO (US) 2000-03-22 CN disclosed
CN-1050618-C Latent Catalysts, Cure-inhibited epxoy resin compositions and laminates prepared therefrom DOW CHEMICAL CO (US) 2000-03-22 CN disclosed
CN-1035823-C Process for preparing latent catalysts for curing epoxy resins DOW CHEMICAL CO (US) 1997-09-10 CN disclosed
EP-0328020-B1 Use of a catalyst in epoxy compositions DOW CHEMICAL CO (US) 1996-10-09 EP disclosed
US-5503937-A MIXTURE OF A COMPOUND HAVING MORE THAN ONE EPOXY GROUP, A DIHYDRIC PHENOLIC COMPOUND AND A LATENT CATALYST COMPRISING A SALT OF AN N-HETEROCYCLIC COMPOUND AND AN ACID HAVING A STRONG NUCLEOPHILIC ANION; COATINGS/MOLDINGS; STORAGE THE DOW CHEMICAL COMPANY (US) 1996-04-02 US disclosed
CN-1118794-A Latent Catalysts, Cure-inhibited epxoy resin compositions and laminates prepared therefrom DOW CHEMICAL CO (US) 1996-03-20 CN disclosed
CN-1118793-A Latent catalysts, cure-inhibited epxoy resin compositions and laminates prepared therefrom DOW CHEMICAL CO (US) 1996-03-20 CN disclosed
EP-0553887-A2 Catalysts and epoxy resin composition containing the same THE DOW CHEMICAL COMPANY (US) 1993-08-04 EP disclosed
US-5169473-A Complex of an onium, arsenic or amine compound and boric acid; advanced polyepoxides; storage stability THE DOW CHEMICAL COMPANY (US) 1992-12-08 US disclosed
US-5134239-A Quaterinary indolizine compound THE DOW CHEMICAL COMPANY (US) 1992-07-28 US disclosed
CN-1056699-A Latent catalysts and cure-inhibited epoxy resin compositions and laminates made therefrom DOW CHEMICAL CO (US) 1991-12-04 CN disclosed
EP-0458502-A2 Latent catalysts, cure-inhibited epoxy resin compositions and laminates prepared therefrom THE DOW CHEMICAL COMPANY (US) 1991-11-27 EP disclosed
US-4925901-A STORAGE STAABILITY, ONIUM ION CATALYST THE DOW CHEMICAL COMPANY (US) 1990-05-15 US disclosed
EP-0328020-A2 Use of a catalyst in epoxy compositions THE DOW CHEMICAL COMPANY (US) 1989-08-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180030264-A1 Benzoxazine Low Temperature Curable Composition CRYZ, PIEZO1, PSMD12 FGFR1 4584/4885CDK2 1695/4885HSP90AA1 550/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.