Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | NOS1 | P29475 | 3/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.53 |
| ▸ | METAP2 | P50579 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.49 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.48 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.48 |
| ▸ | INSR | P06213 | 2/20 | 0.48 |
| ▸ | IGF1R | P08069 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9228890 | 0.85 | MAPT (0.50) | MAPTALDH1A1NOS1DYRK1AMETAP2 | |
| SCHEMBL764032 | 0.85 | CDC7 (0.55) | MAPTALDH1A1NOS1DYRK1AMETAP2 | |
| SCHEMBL8669605 | 0.84 | NOS1 (0.57) | MAPTALDH1A1NOS1DYRK1AMETAP2 | |
| SCHEMBL9228071 | 0.82 | RECQL (0.49) | MAPTALDH1A1NOS1DYRK1AMETAP2 | |
| SCHEMBL21004112 | 0.81 | FGFR1 (0.49) | MAPTALDH1A1NOS1DYRK1AMETAP2 | |
| SCHEMBL28140527 | 0.81 | INSR (0.52) | MAPTALDH1A1NOS1DYRK1AMETAP2 | |
| SCHEMBL20721589 | 0.81 | MAPT (0.53) | MAPTALDH1A1NOS1DYRK1AMETAP2 | |
| SCHEMBL7132606 | 0.81 | NOS1 (0.58) | MAPTALDH1A1NOS1DYRK1AMETAP2 | |
| SCHEMBL29491224 | 0.81 | NOS1 (0.53) | MAPTALDH1A1NOS1DYRK1AMETAP2 | |
| SCHEMBL879376 | 0.81 | NOS1 (0.53) | MAPTALDH1A1NOS1DYRK1AMETAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 247 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017160361-A1 | POLYISOCYANURATE CATALYSTS FOR METAL PANELS AND SPRAY FOAMS | HUNTSMAN PETROCHEMICAL LLC (US) | 2017-09-21 | — | — | WO | claimed |
| EP-4499649-A1 | IKZF2 DEGRADERS AND USES THEREOF | Regents of the University of Michigan (US) | 2025-02-05 | — | — | EP | disclosed |
| US-20240216357-A1 | POLYCYCLIC COMPOUND AND APPLICATION THEREOF | SICHUAN HUIYU PHARMACEUTICAL CO., LTD. (CN) | 2024-07-04 | — | — | US | disclosed |
| US-11771738-B2 | Endoparasitic depsipeptides | ZOETIS SERVICES LLC (US) | 2023-10-03 | — | — | US | disclosed |
| WO-2023183540-A1 | IKZF2 DEGRADERS AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2023-09-28 | — | — | WO | disclosed |
| US-11739098-B2 | Substituted indole compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-08-29 | — | — | US | disclosed |
| US-11673887-B2 | N-acyl amino acid compounds and methods of use | PLIANT THERAPEUTICS, INC. (US) | 2023-06-13 | — | — | US | disclosed |
| US-20230174523-A1 | BENZENESULFONAMIDE DERIVATIVES AS TRAP1 MODULATORS AND USES THEREOF | AMATHUS THERAPEUTICS, INC. (US) | 2023-06-08 | — | — | US | disclosed |
| US-20230027026-A1 | FUSED PYRIMIDINE COMPOUNDS, COMPOSITIONS AND MEDICINAL APPLICATIONS THEREOF | BLUEPRINT MEDICINES CORPORATION | 2023-01-26 | — | — | US | disclosed |
| US-20230012655-A1 | URIDINE DIPHOSPHATE DERIVATIVES, PRODRUGS, COMPOSITIONS AND USES THEREOF | UNIV TUFTS (US) | 2023-01-19 | — | — | US | disclosed |
| US-5376152-A | Heterocyclic nitrogen compound mannich base derivatives of polyolefin-substituted amines for oleaginous compositions | EXXON CHEMICAL PATENTS INC. (US) | 1994-12-27 | — | — | US | disclosed |
| EP-0518949-B1 | NOVEL HETEROCYCLIC NITROGEN COMPOUND MANNICH BASE DERIVATIVES OF AMINO-SUBSTITUTED POLYMERS FOR OLEAGINOUS COMPOSITIONS | EXXON CHEMICAL PATENTS INC (US) | 1994-06-22 | — | — | EP | disclosed |
| US-5273671-A | Reaction product of ethylene/alpha-olefin copolymer, polyamine, aldehyde and a benzotriazole or benzimidazole | EXXON CHEMICAL PATENTS INC. (US) | 1993-12-28 | — | — | US | disclosed |
| US-5271856-A | Heterocyclic nitrogen compound Mannich base derivatives of amino-substituted polymers for oleaginous compositions | EXXON CHEMICAL PATENTS INC. (US) | 1993-12-21 | — | — | US | disclosed |
| US-5232615-A | Reacting an amine with halogenated polyolefin to form adduct and contacting adduct with an aldehyde and a heterocyclic reactant to form an oil soluble, oxidation resistance dispersant for fuels | EXXON CHEMICAL PATENTS INC. (US) | 1993-08-03 | — | — | US | disclosed |
| US-5211865-A | Oil soluble ethylene copolymer with alpha-olefin and grafted carboxylic acid and anhydride with polyamine, an anhydride and heterocycle | EXXON CHEMICAL PATENTS INC. (US) | 1993-05-18 | — | — | US | disclosed |
| EP-0520012-A1 | IMPROVED MULTIFUNCTIONAL VISCOSITY INDEX IMPROVER-DISPERSANT ANTIOXIDANT (PT-789). | EXXON CHEMICAL PATENTS INC (US) | 1992-12-30 | — | — | EP | disclosed |
| EP-0518949-A1 | NOVEL HETEROCYCLIC NITROGEN COMPOUND MANNICH BASE DERIVATIVES OF AMINO-SUBSTITUTED POLYMERS FOR OLEAGINOUS COMPOSITIONS. | EXXON CHEMICAL PATENTS INC (US) | 1992-12-23 | — | — | EP | disclosed |
| WO-1991013954-A1 | NOVEL HETEROCYCLIC NITROGEN COMPOUND MANNICH BASE DERIVATIVES OF AMINO-SUBSTITUTED POLYMERS FOR OLEAGINOUS COMPOSITIONS | EXXON CHEMICAL PATENTS INC. (US) | 1991-09-19 | — | — | WO | disclosed |
| WO-1991013952-A1 | IMPROVED MULTIFUNCTIONAL VISCOSITY INDEX IMPROVER-DISPERSANT ANTIOXIDANT (PT-789) | EXXON CHEMICAL PATENTS INC. (US) | 1991-09-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11673887-B2 | N-acyl amino acid compounds and methods of use | ITGA1, ITGB1, ITGAL | MAPT 4142/4885ALDH1A1 524/4885NOS1 796/4885 |
| US-20230174523-A1 | BENZENESULFONAMIDE DERIVATIVES AS TRAP1 MODULATORS AND USES THEREOF | TRAP1, PINK1, TP53BP1 | MAPT 89/4885ALDH1A1 2569/4885NOS1 1325/4885 |
| US-11771738-B2 | Endoparasitic depsipeptides | VIP, PREP, VIPR1 | MAPT 4773/4885ALDH1A1 2109/4885NOS1 2071/4885 |
| US-20230012655-A1 | URIDINE DIPHOSPHATE DERIVATIVES, PRODRUGS, COMPOSITIONS AND USES THEREOF | UMPS, UPP1, UGDH | MAPT 56/4885ALDH1A1 1514/4885NOS1 939/4885 |
| US-20240216357-A1 | POLYCYCLIC COMPOUND AND APPLICATION THEREOF | KDM1A, TET1, KDM3A | MAPT 138/4885ALDH1A1 460/4885NOS1 3190/4885 |
| US-11739098-B2 | Substituted indole compounds | TLR7, TLR1, HTR7 | MAPT 4681/4885ALDH1A1 2474/4885NOS1 405/4885 |
| US-20230027026-A1 | FUSED PYRIMIDINE COMPOUNDS, COMPOSITIONS AND MEDICINAL APPLICATIONS THEREOF | DPYD, TYMP, TYMS | MAPT 77/4885ALDH1A1 953/4885NOS1 4557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.