Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.52 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PLK1 | P53350 | 3/20 | 0.47 |
| ▸ | PLK3 | Q9H4B4 | 3/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7068038 | 1.00 | TBXAS1 (0.52) | TBXAS1TRPV1CYP4Z1MAPTL3MBTL1 | |
| SCHEMBL7071393 | 1.00 | TBXAS1 (0.52) | TBXAS1TRPV1CYP4Z1MAPTL3MBTL1 | |
| SCHEMBL7126453 | 0.82 | MAPT (0.54) | CYP4Z1MAPTL3MBTL1ADRB1HTT | |
| SCHEMBL9368933 | 0.82 | CYP3A4 (0.63) | CYP4Z1MAPTL3MBTL1ADRB1ADRB2 | |
| SCHEMBL7068530 | 0.80 | NAAA (0.63) | CYP4Z1L3MBTL1MAPK1HTTSMN1; SMN2 | |
| SCHEMBL13754056 | 0.78 | PLK1 (0.65) | TRPV1MAPTPLK1 | |
| Dodecane SCHEMBL27685946 | 0.78 | CYP3A4 (0.72) | TBXAS1MAPT | |
| SCHEMBL8508590 | 0.78 | CYP4Z1 (0.65) | TBXAS1CYP4Z1MAPTL3MBTL1ADRB1 | |
| SCHEMBL7071390 | 0.77 | CYP24A1 (0.74) | — | |
| SCHEMBL7068036 | 0.77 | CYP24A1 (0.74) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003045381-A1 | AMINOALKYLIMIDAZOLE DERIVATIVES AND THEIR USE IN MEDICINE | MOLECULAR SKINCARE LIMITED (GB) | 2003-06-05 | — | — | WO | claimed |
| WO-2003045381-A1 | AMINOALKYLIMIDAZOLE DERIVATIVES AND THEIR USE IN MEDICINE | MOLECULAR SKINCARE LIMITED (GB) | 2003-06-05 | — | — | WO | disclosed |