Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | ADH5 | P11766 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4674989 | 0.89 | CYP3A4 (0.60) | CYP3A4BAZ2BHTTCYP4Z1MAPT | |
| SCHEMBL7126453 | 0.87 | MAPT (0.54) | CYP3A4BAZ2BHTTCYP4Z1MAPT | |
| SCHEMBL7068530 | 0.84 | NAAA (0.63) | CYP3A4BAZ2BHTTCYP4Z1L3MBTL1 | |
| SCHEMBL9363661 | 0.84 | ALDH1A1 (0.58) | CYP3A4BAZ2BHTTCYP4Z1MAPT | |
| SCHEMBL10960777 | 0.83 | CYP3A4 (0.64) | CYP3A4BAZ2BHTTCYP4Z1MAPT | |
| Hydrochloric Acid SCHEMBL9363955 | 0.83 | BLM (0.59) | CYP3A4BAZ2BHTTCYP4Z1MAPT | |
| SCHEMBL8781065 | 0.83 | CYP4Z1 (0.57) | CYP3A4BAZ2BHTTCYP4Z1MAPT | |
| SCHEMBL9363630 | 0.82 | DRD3 (0.55) | CYP3A4BAZ2BHTTCYP4Z1LMNA | |
| Hydrochloric Acid SCHEMBL8781047 | 0.82 | CYP4Z1 (0.56) | CYP3A4BAZ2BHTTCYP4Z1MAPT | |
| SCHEMBL7072586 | 0.82 | TBXAS1 (0.52) | HTTCYP4Z1MAPTL3MBTL1ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0290377-B1 | Substituted 4-[1H-Imidazol-1-yl] benzamides as antiarrhythmic agents | SCHERING AG (DE) | 1994-03-02 | — | — | EP | disclosed |
| EP-0290377-A1 | Substituted 4-[1H-Imidazol-1-yl] benzamides as antiarrhythmic agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-11-09 | — | — | EP | disclosed |