Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.54 |
| ▸ | CYP24A1 | Q07973 | 3/20 | 0.52 |
| ▸ | CYP27B1 | O15528 | 2/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.52 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.49 |
| ▸ | LSS | P48449 | 1/20 | 0.48 |
| ▸ | ADH5 | P11766 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9368933 | 0.87 | CYP3A4 (0.63) | MAPTL3MBTL1CYP4Z1ADRB1CYP3A4 | |
| SCHEMBL7068038 | 0.82 | TBXAS1 (0.52) | MAPTL3MBTL1CYP4Z1ADRB1HTT | |
| SCHEMBL7071393 | 0.82 | TBXAS1 (0.52) | MAPTL3MBTL1CYP4Z1ADRB1HTT | |
| SCHEMBL7072586 | 0.82 | TBXAS1 (0.52) | MAPTL3MBTL1CYP4Z1ADRB1HTT | |
| SCHEMBL4674989 | 0.77 | CYP3A4 (0.60) | MAPTL3MBTL1CYP4Z1ADRB1CYP3A4 | |
| SCHEMBL8508590 | 0.76 | CYP4Z1 (0.65) | MAPTL3MBTL1CYP4Z1ADRB1ADH5 | |
| SCHEMBL4146583 | 0.76 | MEN1 (0.69) | MAPTL3MBTL1HTTSMN1; SMN2 | |
| SCHEMBL8795454 | 0.74 | DRD3 (0.58) | ADRB1CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL5947724 | 0.74 | EPHX2 (0.64) | MAPTL3MBTL1CYP4Z1ADRB1ADH5 | |
| SCHEMBL7068530 | 0.73 | NAAA (0.63) | L3MBTL1CYP4Z1CYP3A4HTTBAZ2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003045381-A1 | AMINOALKYLIMIDAZOLE DERIVATIVES AND THEIR USE IN MEDICINE | MOLECULAR SKINCARE LIMITED (GB) | 2003-06-05 | — | — | WO | claimed |
| WO-2003045381-A1 | AMINOALKYLIMIDAZOLE DERIVATIVES AND THEIR USE IN MEDICINE | MOLECULAR SKINCARE LIMITED (GB) | 2003-06-05 | — | — | WO | disclosed |