Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3366949 | 0.85 | KMT2A (0.70) | KMT2AL3MBTL1NPC1RAB9AFFAR1 | |
| Water SCHEMBL3678915 | 0.84 | KMT2A (0.68) | KMT2AL3MBTL1NPC1RAB9AFFAR1 | |
| Hydrochloric Acid SCHEMBL3136984 | 0.84 | KMT2A (0.68) | KMT2AL3MBTL1NPC1RAB9AFFAR1 | |
| SCHEMBL7071088 | 0.82 | FFAR1 (0.69) | L3MBTL1MAPTSRD5A2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL9130864 | 0.82 | KMT2A (0.66) | KMT2AL3MBTL1NPC1RAB9AFFAR1 | |
| SCHEMBL7071029 | 0.79 | CYP4F2 (0.59) | KMT2AL3MBTL1MAPTSRD5A2NPC1 | |
| SCHEMBL12065143 | 0.79 | L3MBTL1 (0.62) | KMT2AL3MBTL1MAPTSRD5A2NPC1 | |
| SCHEMBL7088866 | 0.79 | FFAR1 (0.65) | KMT2AL3MBTL1FFAR1MEN1HTT | |
| SCHEMBL8896718 | 0.79 | NPC1 (0.59) | KMT2AL3MBTL1MAPTSRD5A2NPC1 | |
| SCHEMBL7069304 | 0.79 | SIGMAR1 (0.56) | L3MBTL1MAPTSRD5A2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1179940-C | Novel 1,2-diphenyl-2-propen-1-one derivatives | ������ҩ��ʽ���� | 2004-12-15 | — | — | CN | disclosed |
| EP-1142865-B1 | NOVEL 1,2-DIPHENYL-2-PROPEN-1-ONE DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2003-06-18 | — | — | EP | disclosed |
| US-6395932-B1 | AMINOALKYL-1,2-DIPHENYL-2-PROPEN-1-ONE WHICH LOWER INTRAOCULAR PRESSURE BY CAUSING MORPHOLOGICAL CHANGE IN TRABECULAR MESHWORK CELLS. | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-05-28 | — | — | US | disclosed |
| CN-1336910-A | Novel 1,2-diphenyl-2-propen-1-one derivatives | SANTEN PHARMACEUTICAL CO LTD (JP) | 2002-02-20 | — | — | CN | disclosed |
| EP-1142865-A1 | NOVEL 1,2-DIPHENYL-2-PROPEN-1-ONE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |