Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | DPYD | Q12882 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HBB | P68871 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4353311 | 0.87 | DPYD (0.50) | LMNADPYDGAAATAD2ALDH1A1 | |
| SCHEMBL2584919 | 0.83 | LMNA (0.52) | LMNADPYDGAAATAD2ALDH1A1 | |
| SCHEMBL2320491 | 0.79 | ALDH1A1 (0.48) | LMNADPYDGAAATAD2ALDH1A1 | |
| SCHEMBL7070324 | 0.79 | GAA (0.50) | LMNADPYDGAAATAD2ALDH1A1 | |
| SCHEMBL156784 | 0.79 | ATAD2 (0.48) | ATAD2 | |
| SCHEMBL5800398 | 0.78 | — | — | |
| SCHEMBL17504388 | 0.77 | GAA (0.41) | LMNADPYDGAAMAPT | |
| SCHEMBL356483 | 0.76 | TYMP (0.49) | ATAD2 | |
| SCHEMBL7599681 | 0.76 | ALDH1A1 (0.45) | LMNADPYDGAAATAD2ALDH1A1 | |
| SCHEMBL161148 | 0.76 | ATAD2 (0.54) | LMNADPYDGAAATAD2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5177064-A | TARGETED DRUG DELIVERY VIA PHOSPHONATE DERIVATIVES | UNIVERSITY OF FLORIDA (US) | 1993-01-05 | — | — | US | claimed |
| EP-0880539-B1 | NUCLEOSIDE ANALOGUES | AMERSHAM BIOSCIENCES UK LTD (GB) | 2003-06-25 | — | — | EP | disclosed |
| US-6313286-B1 | NUCLEOSIDE WITH DEGENERATE BASE AND REPORTER MOLECULE; FOR INCORPORATION INTO OLIGONUCLEOTIDES AS LABELS; HYBRIDIZATION; IMMUNOASSAY | AMERSHAM PHARMACIA BIOTECH UK LIMITED (GB) | 2001-11-06 | — | — | US | disclosed |
| EP-0880539-A1 | NUCLEOSIDE ANALOGUES | Amersham Pharmacia Biotech UK Limited (GB) | 1998-12-02 | — | — | EP | disclosed |
| WO-1997028177-A1 | NUCLEOSIDE ANALOGUES | AMERSHAM PHARMACIA BIOTECH UK LIMITED (GB) | 1997-08-07 | — | — | WO | disclosed |
| EP-0421777-B1 | Further antiviral pyrimidine nucleosides | UNIV BIRMINGHAM (GB) | 1996-02-28 | — | — | EP | disclosed |
| EP-0658166-A1 | ANTIVIRAL PYRIMIDINE NUCLEOSIDES | THE UNIVERSITY OF BIRMINGHAM (GB) | 1995-06-21 | — | — | EP | disclosed |
| WO-1994005687-A1 | ANTIVIRAL PYRIMIDINE NUCLEOSIDES | UNIVERSITY OF BIRMINGHAM (GB) | 1994-03-17 | — | — | WO | disclosed |
| EP-0514036-A2 | Preparation of thionucleosides | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-11-19 | — | — | EP | disclosed |
| WO-1991004982-A1 | FURTHER ANTIVIRAL PYRIMIDINE NUCLEOSIDES | UNIVERSITY OF BIRMINGHAM (GB) | 1991-04-18 | — | — | WO | disclosed |
| EP-0421777-A1 | Further antiviral pyrimidine nucleosides | THE UNIVERSITY OF BIRMINGHAM (GB) | 1991-04-10 | — | — | EP | disclosed |
| WO-1984000759-A1 | DESOXYURIDINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | SANDOZ AG (AT) | 1984-03-01 | — | — | WO | disclosed |