SCHEMBL2584919

SCHEMBL2584919

O=c1[nH]cc(CCl)c(=O)[nH]1

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.52
ALDH1A1 P00352 1/20 0.52
MAPT P10636 1/20 0.52
CYP19A1 P11511 1/20 0.52
TSHR P16473 1/20 0.52
THPO P40225 1/20 0.52
MTOR P42345 1/20 0.52
HTT P42858 1/20 0.52
HBB P68871 1/20 0.52
PMP22 Q01453 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
DPYD Q12882 1/20 0.46
GAA P10253 1/20 0.46
ATAD2 Q6PL18 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7074433 0.83 LMNA (0.43) LMNAALDH1A1MAPTCYP19A1TSHR
SCHEMBL5800398 0.81
SCHEMBL4353311 0.81 DPYD (0.50) LMNAALDH1A1MAPTCYP19A1TSHR
SCHEMBL161148 0.79 ATAD2 (0.54) LMNAALDH1A1MAPTCYP19A1TSHR
SCHEMBL5798297 0.77 DPYD (0.46) LMNAALDH1A1MAPTCYP19A1TSHR
SCHEMBL1916592 0.77 DPYD (0.46) LMNAALDH1A1MAPTCYP19A1TSHR
SCHEMBL6555485 0.77 DPYD (0.52) LMNAALDH1A1MAPTCYP19A1TSHR
SCHEMBL44459 0.77 GAA (0.52) LMNAALDH1A1MAPTCYP19A1TSHR
SCHEMBL4625879 0.77 ALDH1A1 (0.52) LMNAALDH1A1MAPTCYP19A1TSHR
SCHEMBL2037916 0.77 DPYD (0.46) LMNAALDH1A1MAPTCYP19A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119241503-A Compound, fluorophore and immunofluorophore as well as preparation methods and application thereof 辽宁警察学院 2025-01-03 CN claimed
CN-106632081-A 5-chloro-6-(chloromethyl) uracil and preparation method thereof 四川同晟生物医药有限公司 2017-05-10 CN claimed
WO-2013090873-A1 A COMPOSITION AND METHOD FOR REDUCING CYANURIC ACID IN RECREATIONAL WATER HAVILAND PRODUCTS COMPANY (US) 2013-06-20 WO claimed
EP-0898575-B1 A COMBINATORIAL PROTECTING GROUP STRATEGY FOR MULTIFUNCTIONAL MOLECULES KOESTER HUBERT DR (US) 2004-12-29 EP claimed
US-20030194741-A1 COMBINATORIAL PROTECTING GROUP STRATEGY FOR MULTIFUNCTIONAL MOLECULES CAPROTEC BIOANALYTICS GMBH (DE) 2003-10-16 US claimed
EP-0898575-A2 A COMBINATORIAL PROTECTING GROUP STRATEGY FOR MULTIFUNCTIONAL MOLECULES KÖSTER, Hubert (US) 1999-03-03 EP claimed
WO-1997041139-A2 A COMBINATORIAL PROTECTING GROUP STRATEGY FOR MULTIFUNCTIONAL MOLECULES KOESTER HUBERT (US) 1997-11-06 WO claimed
CN-119241503-A Compound, fluorophore and immunofluorophore as well as preparation methods and application thereof 辽宁警察学院 2025-01-03 CN disclosed
WO-2024030429-A1 BASE-MODIFIED RIBONUCLEOSIDES AS PRODRUGS AGAINST VIRAL AND BACTERIAL INFECTIONS THE UNITED STATES GOVERNMENT, AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 2024-02-08 WO disclosed
WO-2024030429-A1 BASE-MODIFIED RIBONUCLEOSIDES AS PRODRUGS AGAINST VIRAL AND BACTERIAL INFECTIONS THE UNITED STATES GOVERNMENT, AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 2024-02-08 WO disclosed
CN-113024547-B Bicyclic heterocycles as FGFR4 inhibitors 因赛特控股公司 2023-07-21 CN disclosed
US-11667635-B2 Bicyclic heterocycles as FGFR4 inhibitors INCYTE CORPORATION (US) 2023-06-06 US disclosed
US-20220009921-A1 BICYCLIC HETEROCYCLES AS FGFR4 INHIBITORS INCYTE CORPORATION 2022-01-13 US disclosed
US-4564616-A Anti-cancer quinazoline derivatives NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1986-01-14 US disclosed
US-4526965-A Uracil derivatives of thio- and selenourea compounds POLAROID CORPORATION (US) 1985-07-02 US disclosed
US-4447608-A ANTITUMOR AGENTS NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1984-05-08 US disclosed
US-4442290-A DERIVATIVES OF PYRIMIDINEDIONE POLAROID CORPORATION (US) 1984-04-10 US disclosed
EP-0071282-A2 Uracil derivatives and use thereof in photographic products and processes POLAROID CORPORATION (US) 1983-02-09 EP disclosed
US-4350754-A FOR PHOTOGRAPHIC FILMS; URACIL DERIVATIVES POLAROID CORPORATION (US) 1982-09-21 US disclosed
EP-0031237-A1 Quinazoline derivatives, processes for their preparation, compositions containing them and their use as anti-cancer agents NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1981-07-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030194741-A1 COMBINATORIAL PROTECTING GROUP STRATEGY FOR MULTIFUNCTIONAL MOLECULES ADAR, RNMT, ATIC LMNA 2407/4885ALDH1A1 4111/4885MAPT 2388/4885
US-11667635-B2 Bicyclic heterocycles as FGFR4 inhibitors FGFR4, FGFR1, FGFR3 LMNA 4388/4885ALDH1A1 901/4885MAPT 3789/4885
US-20220009921-A1 BICYCLIC HETEROCYCLES AS FGFR4 INHIBITORS FGFR4, FGFR1, FGFR3 LMNA 4388/4885ALDH1A1 901/4885MAPT 3789/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.