Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 3/20 | 0.44 |
| ▸ | MAP3K9 | P80192 | 2/20 | 0.44 |
| ▸ | MAP3K11 | Q16584 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD5 | P21918 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20402086 | 0.82 | DRD2 (0.39) | LIMK1MAP3K9MAP3K11CA1CA2 | |
| SCHEMBL16546076 | 0.82 | GPR3 (0.39) | LIMK1MAP3K9MAP3K11CA1CA2 | |
| SCHEMBL12013258 | 0.80 | GPR3 (0.52) | LIMK1DRD2DRD1DRD4DRD5 | |
| SCHEMBL13959740 | 0.79 | GPR3 (0.37) | LIMK1MAP3K9MAP3K11CA1CA2 | |
| SCHEMBL13959766 | 0.79 | DRD2 (0.36) | LIMK1MAP3K9MAP3K11CA1CA2 | |
| SCHEMBL17792031 | 0.77 | KDM4E (0.42) | GPR3L3MBTL1 | |
| SCHEMBL7081563 | 0.77 | CA1 (0.45) | CA1CA2CA4CA6DRD2 | |
| Fluorene SCHEMBL17889181 | 0.76 | GPR3 (0.61) | LIMK1MAP3K9MAP3K11CA1CA2 | |
| SCHEMBL17010907 | 0.76 | LIMK1 (0.49) | LIMK1MAP3K9MAP3K11CA1CA2 | |
| SCHEMBL13959784 | 0.76 | GPR3 (0.37) | LIMK1MAP3K9MAP3K11DRD2DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116120277-A | Synthesis method of 10H-benzo [ b ] indeno [2,1-d ] thiophene-10-ketone compound | 陕西师范大学 | 2023-05-16 | — | — | CN | claimed |
| JP-10109985-A | — | — | None | — | — | JP | disclosed |
| CN-116120277-B | Synthesis method of 10H-benzo [ b ] indeno [2,1-d ] thiophene-10-ketone compound | 陕西师范大学 | 2024-04-05 | — | — | CN | disclosed |
| CN-116120277-B | Synthesis method of 10H-benzo [ b ] indeno [2,1-d ] thiophene-10-ketone compound | 陕西师范大学 | 2024-04-05 | — | — | CN | disclosed |
| CN-116120277-B | Synthesis method of 10H-benzo [ b ] indeno [2,1-d ] thiophene-10-ketone compound | 陕西师范大学 | 2024-04-05 | — | — | CN | disclosed |
| CN-116120277-A | Synthesis method of 10H-benzo [ b ] indeno [2,1-d ] thiophene-10-ketone compound | 陕西师范大学 | 2023-05-16 | — | — | CN | disclosed |
| CN-116120277-A | Synthesis method of 10H-benzo [ b ] indeno [2,1-d ] thiophene-10-ketone compound | 陕西师范大学 | 2023-05-16 | — | — | CN | disclosed |
| CN-116120277-A | Synthesis method of 10H-benzo [ b ] indeno [2,1-d ] thiophene-10-ketone compound | 陕西师范大学 | 2023-05-16 | — | — | CN | disclosed |
| US-10370473-B2 | Compound, curable composition, cured product, optical member, and lens | FUJIFILM CORPORATION (JP) | 2019-08-06 | — | — | US | disclosed |
| US-8252883-B2 | Silicon cluster substituted with a conductive organic material; thin film transistor | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2012-08-28 | — | — | US | disclosed |
| US-20080076872-A1 | Organic semiconductor composition comprising oligomer compounds, composition for patterning organic smiconductor layer comprising the same, organic semiconductor thin film using the same and organic electronic device employing the thin film | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2008-03-27 | — | — | US | disclosed |
| US-20070287220-A1 | Organic semiconductor materials using stacking-inducing compounds, compositions comprising such materials, organic semiconductor thin films formed using such compositions, and organic electronic devices incorporating such thin films | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2007-12-13 | — | — | US | disclosed |
| US-20070287220-A1 | Organic semiconductor materials using stacking-inducing compounds, compositions comprising such materials, organic semiconductor thin films formed using such compositions, and organic electronic devices incorporating such thin films | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2007-12-13 | — | — | US | disclosed |
| EP-0832890-B1 | Benzo (B) indeno (2,1-D) thiophene compounds, intermediates, processes, compositions, and methods | LILLY CO ELI (US) | 2003-07-02 | — | — | EP | disclosed |
| EP-0832890-B1 | Benzo (B) indeno (2,1-D) thiophene compounds, intermediates, processes, compositions, and methods | LILLY CO ELI (US) | 2003-07-02 | — | — | EP | disclosed |
| US-6133458-A | FOR INHIBITING BONE LOSS OR BONE RESORPTION, PARTICULARLY OSTEOPOROSIS, CARDIOVASCULAR-RELATED PATHOLOGICAL CONDITIONS INCLUDING HYPERLIPIDEMIA AND RELATED CARDIOVASCULAR PATHOLOGIES, AND ESTROGEN-DEPENDENT CANCER | ELI LILLY AND COMPANY (US) | 2000-10-17 | — | — | US | disclosed |
| US-6133458-A | FOR INHIBITING BONE LOSS OR BONE RESORPTION, PARTICULARLY OSTEOPOROSIS, CARDIOVASCULAR-RELATED PATHOLOGICAL CONDITIONS INCLUDING HYPERLIPIDEMIA AND RELATED CARDIOVASCULAR PATHOLOGIES, AND ESTROGEN-DEPENDENT CANCER | ELI LILLY AND COMPANY (US) | 2000-10-17 | — | — | US | disclosed |
| JP-H10109985-A | BENZO(B)INDENO(2,1-D) THIOPHENE COMPOUND, ITS INTERMEDIATE, ITS PRODUCTION, ITS COMPOSITION, AND ITS USING METHOD | ELI LILLY & CO | 1998-04-28 | — | — | JP | disclosed |
| EP-0832890-A1 | Benzo (B) indeno (2,1-D) thiophene compounds, intermediates, processes, compositions, and methods | ELI LILLY AND COMPANY (US) | 1998-04-01 | — | — | EP | disclosed |
| EP-0832890-A1 | Benzo (B) indeno (2,1-D) thiophene compounds, intermediates, processes, compositions, and methods | ELI LILLY AND COMPANY (US) | 1998-04-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10370473-B2 | Compound, curable composition, cured product, optical member, and lens | CRYZ, CRYAA, UACA | LIMK1 2686/4885MAP3K9 4557/4885MAP3K11 4369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.