Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7078457 | 0.88 | SLC6A5 (0.42) | MEN1KMT2A | |
| SCHEMBL6950872 | 0.86 | HTT (0.45) | MEN1KMT2ASLC6A4SLC6A3 | |
| SCHEMBL7083199 | 0.83 | REN (0.46) | MEN1KMT2A | |
| SCHEMBL6954030 | 0.83 | MAPT (0.39) | — | |
| SCHEMBL5562101 | 0.83 | MEN1 (0.39) | MEN1KMT2ASLC6A4SLC6A3 | |
| SCHEMBL4602631 | 0.83 | MEN1 (0.39) | MEN1KMT2ASLC6A4SLC6A3 | |
| SCHEMBL6949144 | 0.83 | GPR119 (0.39) | MEN1KMT2A | |
| SCHEMBL6952811 | 0.83 | PDE4B (0.50) | MEN1KMT2ASLC6A4SLC6A3 | |
| SCHEMBL6956400 | 0.83 | SLC6A4 (0.39) | SLC6A4SLC6A3 | |
| SCHEMBL6950896 | 0.83 | RIPK1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863875-B1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | HOFFMANN LA ROCHE (CH) | 2003-06-04 | — | — | EP | disclosed |
| EP-0863875-A1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | F. HOFFMANN-LA ROCHE AG (CH) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997009311-A1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | F. HOFFMANN-LA ROCHE AG (CH) | 1997-03-13 | — | — | WO | disclosed |