SCHEMBL707583

SCHEMBL707583

CCN=C=Nc1ccc(N=C=NCC)cc1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 1/20 0.34
▸ TSHR P16473 1/20 0.34
▸ P2RY6 Q15077 1/20 0.34
▸ CYP1A2 P05177 1/20 0.32
▸ CYP2D6 P10635 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18245040 0.91 NOS3 (0.36) CYP3A4TSHRP2RY6CYP2D6
SCHEMBL1009278 0.88 MIF (0.44) CYP3A4TSHR
SCHEMBL12865537 0.87 HSD17B10 (0.32) —
SCHEMBL28208361 0.85 NOS1 (0.46) CYP3A4TSHRP2RY6
SCHEMBL18245135 0.81 MAPT (0.47) —
SCHEMBL30108401 0.80 CYP3A4 (0.32) CYP3A4CYP1A2CYP2D6
SCHEMBL4956648 0.80 CYP3A4 (0.32) CYP3A4CYP1A2CYP2D6
Pyridine SCHEMBL7848227 0.78 MIF (0.36) TSHR
Methacrylic Acid SCHEMBL29034360 0.75 NPC1 (0.36) TSHR
Methacrylic Acid SCHEMBL26103967 0.74 ALDH1A1 (0.37) CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 268 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4289901-A2 THERMOFORMED ARTICLE Novamont S.p.A. (IT) 2023-12-13 — — EP claimed
EP-4032953-B1 THERMOFORMED ARTICLE NOVAMONT SPA (IT) 2023-12-06 — — EP claimed
CN-113906055-B Crosslinked polymers of functionalized hyaluronic acid and their use in the treatment of inflammatory states 卓英医疗有限责任公司 2023-09-26 — — CN claimed
US-11767425-B2 Polymer composition for the manufacture of thermoformed articles NOVAMONT S.P.A. (IT) 2023-09-26 — — US claimed
CN-115651371-A Polymer composition for making thermoformed articles 诺瓦蒙特股份公司 2023-01-31 — — CN claimed
CN-115505244-A Polymer composition for making thermoformed articles 诺瓦蒙特股份公司 2022-12-23 — — CN claimed
US-20220372278-A1 POLYMER COMPOSITION FOR THE MANUFACTURE OF THERMOFORMED ARTICLES NOVAMONT S.P.A. (IT) 2022-11-24 — — US claimed
US-11434363-B2 Polymer composition for the manufacture of thermoformed articles NOVAMONT S.P.A. (IT) 2022-09-06 — — US claimed
US-20220213233-A1 CROSSLINKED POLYMER OF FUNCTIONALIZED HYALURONIC ACID AND ITS USE IN THE TREATMENT OF INFLAMMATORY STATES JOINTHERAPEUTICS S.R.L. (IT) 2022-07-07 — — US claimed
EP-3328941-B1 POLYMER COMPOSITION FOR THE MANUFACTURE OF THERMOFORMED ARTICLES NOVAMONT SPA (IT) 2022-04-13 — — EP claimed
US-20180223095-A1 POLYMER COMPOSITION FOR THE MANUFACTURE OF THERMOFORMED ARTICLES NOVAMONT S.P.A. (IT) 2018-08-09 — — US claimed
EP-3328941-A1 POLYMER COMPOSITION FOR THE MANUFACTURE OF THERMOFORMED ARTICLES Novamont S.p.A. (IT) 2018-06-06 — — EP claimed
EP-1699500-B1 CROSSLINKED HYALURONIC ACID COMPOSITIONS FOR TISSUE AUGMENTATION ANIKA THERAPEUTICS INC (US) 2018-02-21 — — EP claimed
WO-2017021338-A1 POLYMER COMPOSITION FOR THE MANUFACTURE OF THERMOFORMED ARTICLES NOVAMONT S.P.A. (IT) 2017-02-09 — — WO claimed
EP-1305064-B1 BIOABSORBABLE COMPOSITES OF DERIVATIZED HYALURONIC ACID ANIKA THERAPEUTICS INC (US) 2008-04-23 — — EP claimed
EP-1699500-A1 CROSSLINKED HYALURONIC ACID COMPOSITIONS FOR TISSUE AUGMENTATION Anika Therapeutics Inc. (US) 2006-09-13 — — EP claimed
WO-2005067994-A1 CROSSLINKED HYALURONIC ACID COMPOSITIONS FOR TISSUE AUGMENTATION ANIKA THERAPEUTICS, INC. (US) 2005-07-28 — — WO claimed
US-20050136122-A1 Crosslinked hyaluronic acid compositions for tissue augmentation ANIKA THERAPEUTICS, INC. (US) 2005-06-23 — — US claimed
US-6548081-B2 Hyaluronic acid derivative is an N-acylurea that results from crosslinking hyaluronic acid with a multifunctional carbodiimide. reducing post-operative adhesion of tissues. ANIKA THERAPEUTICS, INC. 2003-04-15 — — US claimed
US-20020071855-A1 Bioabsorbable composites of derivatized hyaluronic acid and other biodegradable, biocompatible polymers ANIKA THERAPEUTICS, INC 2002-06-13 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050136122-A1 Crosslinked hyaluronic acid compositions for tissue augmentation H1-0, H1-2, CD44 CYP3A4 3278/4885TSHR 1690/4885P2RY6 959/4885
US-20220213233-A1 CROSSLINKED POLYMER OF FUNCTIONALIZED HYALURONIC ACID AND ITS USE IN THE TREATMENT OF INFLAMMATORY STATES LGALS1, LGALS2, LGALS3 CYP3A4 3510/4885TSHR 2103/4885P2RY6 857/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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