SCHEMBL7076176

SCHEMBL7076176

Cc1cccc(C(C(=O)C(c2ccccc2)c2cccc(C)c2)c2ccccc2)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACP3 P15309 1/20 0.54
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.46
ALDH1A1 P00352 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
TDP1 Q9NUW8 2/20 0.44
CTSL P07711 1/20 0.43
CTSB P07858 1/20 0.43
CTSS P25774 1/20 0.43
HDAC3 O15379 1/20 0.42
HDAC4 P56524 1/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC7 Q8WUI4 1/20 0.42
HDAC2 Q92769 1/20 0.42
HDAC10 Q969S8 1/20 0.42
HDAC11 Q96DB2 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
HDAC9 Q9UKV0 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22917247 0.87 ACP3 (0.53) ACP3MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL4619753 0.84 ACP3 (0.53) ACP3MEN1KMT2ASMN1; SMN2HDAC8
SCHEMBL16807284 0.84 L3MBTL1 (0.69) ACP3MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL23031983 0.82 ACP3 (0.49) ACP3MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL7073016 0.82 CNR1 (0.56) MEN1KMT2ASMN1; SMN2ALDH1A1L3MBTL1
SCHEMBL29299753 0.81 L3MBTL1 (0.51) ACP3SMN1; SMN2ALDH1A1L3MBTL1TDP1
SCHEMBL19347281 0.81 ACP3 (0.47) ACP3MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL465969 0.81 TDP1 (0.61) MEN1KMT2AL3MBTL1TDP1HDAC3
SCHEMBL28737154 0.80 ACP3 (0.49) ACP3MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL16807273 0.80 L3MBTL1 (0.62) ACP3MEN1KMT2ASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130116438-A1 IRIDIUM COMPLEX AND METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUND TAKASAGO INTERNATIONAL CORPORATION (JP) 2013-05-09 US disclosed
US-20030120088-A1 Optically active azetidincarboxamide-coordinated transition metal complexes SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-06-26 US disclosed
US-6156940-A Process for producing optically active carbinols SUMIKA FINE CHEMICALS COMPANY, LIMITED (JP) 2000-12-05 US disclosed
EP-0713848-B1 Process for producing optically active carbinols SUMIKA FINE CHEMICALS COMPANY (JP) 1999-09-08 EP disclosed
US-5831132-A REDUCING AGENT FROM BORANES AND AMINO ALCOHOLS SUMIKA FINE CHEMICALS COMPANY, LTD. (JP) 1998-11-03 US disclosed
EP-0713848-A1 Process for producing optically active carbinols SUMIKA FINE CHEMICALS Company, Limited (JP) 1996-05-29 EP disclosed
EP-0435687-B1 Process for isomerization of oxime ethers SUMITOMO CHEMICAL CO (JP) 1995-03-29 EP disclosed
US-5130486-A A ketoximine ether isomerized using a Lewis acid metal halide SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1992-07-14 US disclosed
EP-0435687-A2 Process for isomerization of oxime ethers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-07-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130116438-A1 IRIDIUM COMPLEX AND METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUND PPIP5K2, INF2, IMPDH2 ACP3 282/4885MEN1 898/4885KMT2A 2876/4885
US-20030120088-A1 Optically active azetidincarboxamide-coordinated transition metal complexes AAAS, AP1M1, AP2A1 ACP3 4192/4885MEN1 398/4885KMT2A 1593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.