Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.56 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.56 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301521 | 0.94 | PKM (0.61) | F2PRSS1PRSS2PRSS3PKM | |
| SCHEMBL793287 | 0.80 | PKM (0.59) | PKMALDH1A1KDM4EGAAUSP2 | |
| SCHEMBL6920362 | 0.79 | PKM (0.64) | F2PRSS1PRSS2PRSS3PKM | |
| SCHEMBL7503391 | 0.78 | PTGS2 (0.71) | PKMALDH1A1KDM4EPTGS2PTGS1 | |
| SCHEMBL7078459 | 0.76 | ALDH1A1 (0.48) | F2PRSS1PRSS2PRSS3PKM | |
| SCHEMBL7238460 | 0.76 | PKM (0.59) | PKMALDH1A1KDM4EGAAUSP2 | |
| SCHEMBL6849995 | 0.76 | PTGS2 (0.72) | PKMALDH1A1PTGS2PTGS1CA1 | |
| SCHEMBL2947753 | 0.76 | PKM (0.59) | F2PRSS1PRSS2PRSS3PKM | |
| SCHEMBL14456654 | 0.74 | PKM (0.76) | PKMALDH1A1KDM4EGAAUSP2 | |
| SCHEMBL12883762 | 0.74 | PKM (0.57) | PKMALDH1A1KDM4EUSP2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030144292-A1 | Carbocyclic side chain containing, N-substituted metalloprotease inhibitors | PROCTER & GAMBLE COMPANY, THE | 2003-07-31 | — | — | US | claimed |
| US-20030162778-A1 | Carbocyclic side chain containing metalloprotease inhibitors | THE PROCTER AND GAMBLE COMPANY | 2003-08-28 | — | — | US | disclosed |
| US-20030144292-A1 | Carbocyclic side chain containing, N-substituted metalloprotease inhibitors | PROCTER & GAMBLE COMPANY, THE | 2003-07-31 | — | — | US | disclosed |
| EP-1265887-A2 | CARBOCYCLIC SIDE CHAIN CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2002-12-18 | — | — | EP | disclosed |
| EP-1265886-A2 | CARBOCYCLIC SIDE CHAIN CONTAINING, N-SUBSTITUTED METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2002-12-18 | — | — | EP | disclosed |
| WO-2001070682-A2 | CARBOCYCLIC SIDE CHAIN CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2001-09-27 | — | — | WO | disclosed |
| WO-2001070720-A2 | CARBOCYCLIC SIDE CHAIN CONTAINING, N-SUBSTITUTED METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2001-09-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162778-A1 | Carbocyclic side chain containing metalloprotease inhibitors | MMP2, CMA1, SERPINB1 | F2 687/4885PRSS1 32/4885PRSS2 53/4885 |
| US-20030144292-A1 | Carbocyclic side chain containing, N-substituted metalloprotease inhibitors | MMP2, MMP3, CMA1 | F2 780/4885PRSS1 41/4885PRSS2 56/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.