SCHEMBL707837

SCHEMBL707837

O=C1CC(OCCCCCCI)C(=O)N1

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.42
MAPT P10636 1/20 0.42
PKM P14618 1/20 0.42
NPC1 O15118 1/20 0.34
MAP3K14 Q99558 1/20 0.33
GPR39 O43194 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5318696 0.75 NPC1 (0.44) LMNAMAPTPKMNPC1MAP3K14
SCHEMBL31539133 0.72 MAP3K14 (0.38) LMNAMAPTPKMNPC1MAP3K14
SCHEMBL9510783 0.71 MAP3K14 (0.40) LMNAMAPTPKMNPC1MAP3K14
SCHEMBL1949591 0.69 LMNA (0.41) LMNAMAPTPKMNPC1MAP3K14
SCHEMBL1280223 0.68 LMNA (0.40) LMNAMAPTPKMNPC1MAP3K14
SCHEMBL8348991 0.67 MAP3K14 (0.48) LMNAMAPTPKMNPC1MAP3K14
SCHEMBL10754755 0.67 MAP3K14 (0.48) LMNAMAPTPKMNPC1MAP3K14
SCHEMBL11886046 0.67 MAP3K14 (0.33) LMNAMAPTPKMMAP3K14
SCHEMBL1273192 0.66 MAP3K14 (0.35) LMNAMAPTPKMMAP3K14
SCHEMBL20589363 0.64 PRKCA (0.38) LMNAMAPTPKMMAP3K14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2027453-B1 NONSEPARATION ASSAY METHODS BECKMAN COULTER INC (US) 2017-03-15 EP disclosed
EP-2021778-B1 NONSEPARATION ASSAY METHODS BECKMAN COULTER INC (US) 2017-03-15 EP disclosed
US-8389298-B2 Methods using novel chemiluminescent labels LUMIGEN, INC. (US) 2013-03-05 US disclosed
US-8377647-B2 Nonseparation assay methods BECKMAN COULTER, INC. (US) 2013-02-19 US disclosed
US-20120094313-A1 Nonseparation Assay Methods BECKMAN COULTER, INC. (US) 2012-04-19 US disclosed
US-8124362-B2 Nonseparation assay methods BECKMAN COULTER, INC. (US) 2012-02-28 US disclosed
US-20110318747-A1 Nonseparation Assay Methods BECKMAN COULTER, INC. (US) 2011-12-29 US disclosed
US-20110269156-A1 Nonseparation Assay Methods BECKMAN COULTER, INC. (US) 2011-11-03 US disclosed
US-8012705-B2 Nonseparation assay methods BECKMAN COULTER, INC. (US) 2011-09-06 US disclosed
US-20110183361-A1 Nonseparation Assay Methods BECKMAN COULTER, INC. (US) 2011-07-28 US disclosed
US-7682839-B2 Methods using novel chemiluminescent labels LUMIGEN, INC. (US) 2010-03-23 US disclosed
EP-2021778-A4 NONSEPARATION ASSAY METHODS BECKMAN COULTER INC (US) 2009-07-08 EP disclosed
EP-2027453-A4 NONSEPARATION ASSAY METHODS BECKMAN COULTER INC (US) 2009-07-01 EP disclosed
EP-2027453-A1 NONSEPARATION ASSAY METHODS Beckman Coulter, Inc. (US) 2009-02-25 EP disclosed
EP-2021778-A1 NONSEPARATION ASSAY METHODS Beckman Coulter, Inc. (US) 2009-02-11 EP disclosed
WO-2007134098-A1 NONSEPARATION ASSAY METHODS BECKMAN COULTER, INC. (US) 2007-11-22 WO disclosed
WO-2007133988-A1 NONSEPARATION ASSAY METHODS BECKMAN COULTER, INC. (US) 2007-11-22 WO disclosed
US-20070264664-A1 Nonseparation assay methods NEXGEN DIAGNOSTICS LLC 2007-11-15 US disclosed
US-20070264665-A1 Nonseparation assay methods BECKMAN COULTER, INC. 2007-11-15 US disclosed
US-20070172878-A1 Methods using novel chemiluminescent labels LUMIGEN, INC. 2007-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070172878-A1 Methods using novel chemiluminescent labels HLCS, LANCL1, ACR LMNA 904/4885MAPT 4797/4885PKM 1430/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.