Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7079652 | 0.86 | P2RX7 (0.32) | P2RX7 | |
| SCHEMBL7082454 | 0.85 | — | — | |
| SCHEMBL7079472 | 0.84 | — | — | |
| SCHEMBL7081986 | 0.69 | P2RX7 (0.39) | P2RX7NPC1LMNAGAAHTT | |
| SCHEMBL7080253 | 0.65 | HDAC4 (0.32) | — | |
| SCHEMBL7083525 | 0.64 | P2RX7 (0.33) | P2RX7 | |
| SCHEMBL7085592 | 0.62 | HDAC4 (0.31) | — | |
| SCHEMBL7947348 | 0.60 | HSP90AA1 (0.49) | HSP90AA1NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL7082940 | 0.58 | HSD11B1 (0.51) | — | |
| SCHEMBL7078036 | 0.55 | HDAC4 (0.39) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003064372-A1 | 2-ADAMANTYLALKYLAMINES AND THEIR USE IN THE TREATMENT OF CONDITIONS GENERALLY ASSOCIATED WITH ABNORMALITIES IN GLUTAMATERGIC TRANSMISSION | VERNALIS RESEARCH LIMITED (GB) | 2003-08-07 | — | — | WO | disclosed |