Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7083525 | 0.84 | P2RX7 (0.33) | — | |
| SCHEMBL7082454 | 0.81 | — | — | |
| SCHEMBL7085592 | 0.79 | HDAC4 (0.31) | HDAC4 | |
| SCHEMBL7078036 | 0.78 | HDAC4 (0.39) | HDAC4CYP2D6MEN1KMT2ACNR2 | |
| SCHEMBL7079652 | 0.68 | P2RX7 (0.32) | — | |
| SCHEMBL27599331 | 0.67 | HSD11B1 (0.40) | HDAC4CYP2D6MEN1KMT2ACNR1 | |
| SCHEMBL7079601 | 0.65 | HSP90AA1 (0.33) | — | |
| SCHEMBL1939655 | 0.63 | SLC22A2 (0.30) | — | |
| SCHEMBL6551864 | 0.63 | SLC22A2 (0.30) | — | |
| SCHEMBL677549 | 0.62 | P2RX7 (0.37) | MEN1KMT2ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003064372-A1 | 2-ADAMANTYLALKYLAMINES AND THEIR USE IN THE TREATMENT OF CONDITIONS GENERALLY ASSOCIATED WITH ABNORMALITIES IN GLUTAMATERGIC TRANSMISSION | VERNALIS RESEARCH LIMITED (GB) | 2003-08-07 | — | — | WO | disclosed |