Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2B | P18089 | 1/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | RORC | P51449 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7081755 | 0.85 | ADRA2B (0.60) | ADRA2BTSHRALDH1A1GAACYP3A4 | |
| SCHEMBL4548140 | 0.84 | LMNA (0.69) | TP53ALDH1A1GAAGLAKMT2A | |
| SCHEMBL6646888 | 0.84 | ADRA2B (0.66) | ADRA2BTSHRALDH1A1GAACYP3A4 | |
| SCHEMBL6843412 | 0.83 | PTGDR2 (0.52) | FFAR4TP53RORCTSHRALDH1A1 | |
| SCHEMBL6838344 | 0.82 | ALDH1A1 (0.75) | ADRA2BTSHRALDH1A1GAACYP3A4 | |
| SCHEMBL6645605 | 0.82 | GAA (0.75) | ADRA2BTSHRALDH1A1GAACYP3A4 | |
| SCHEMBL6644866 | 0.81 | ADRA2B (0.57) | ADRA2BTP53TSHRALDH1A1KMT2A | |
| SCHEMBL6643434 | 0.81 | ADRA2B (0.70) | ADRA2BTSHRALDH1A1GAACYP3A4 | |
| SCHEMBL6843458 | 0.80 | ADRA2B (0.65) | ADRA2BNAMPTTSHRALDH1A1GAA | |
| SCHEMBL6646799 | 0.80 | ALDH1A1 (0.67) | ADRA2BTSHRALDH1A1GAACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030073710-A1 | Compounds useful for treatment or prevention of disease mediated by alpha-2B-adrenoceptor | OY JUVANTIA PHARMA LTD (FI) | 2003-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030073710-A1 | Compounds useful for treatment or prevention of disease mediated by alpha-2B-adrenoceptor | ADRB2, ADRB3, ADRB1 | ADRA2B 6/4885FFAR4 939/4885TP53 4843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.