Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7083543 | 1.00 | GABRA1 (0.37) | GABRA1GABRB2ALOX5CA2ADRA1A | |
| SCHEMBL5957049 | 0.78 | HTR1A (0.34) | CA2HTR1A | |
| SCHEMBL6977479 | 0.77 | CA2 (0.42) | ALOX5CA2ADRA1AHTTHTR1A | |
| SCHEMBL6977481 | 0.77 | CA2 (0.42) | ALOX5CA2ADRA1AHTTHTR1A | |
| SCHEMBL6985813 | 0.76 | ADRA1A (0.49) | CA2ADRA1AHTTHTR1AADRA2A | |
| SCHEMBL6981984 | 0.76 | CA2 (0.41) | CA2ADRA1AHTTHTR1AADRA2A | |
| SCHEMBL6985807 | 0.76 | ADRA1A (0.49) | CA2ADRA1AHTTHTR1AADRA2A | |
| SCHEMBL1021052 | 0.76 | ADRA1A (0.47) | CA2ADRA1AHTTHTR1AADRA2A | |
| SCHEMBL6981978 | 0.76 | CA2 (0.41) | CA2ADRA1AHTTHTR1AADRA2A | |
| SCHEMBL6974656 | 0.76 | ADRA1A (0.47) | CA2ADRA1AHTTHTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0928791-B1 | PROCESS FOR PRODUCING 1,4-BENZODIOXANE DERIVATIVES | DAISO CO LTD (JP) | 2003-07-30 | — | — | EP | disclosed |
| US-6020503-A | Process for producing 1,4-benzodioxane derivatives | DAISO CO., LTD. (JP) | 2000-02-01 | — | — | US | disclosed |
| EP-0928791-A1 | PROCESS FOR PRODUCING 1,4-BENZODIOXANE DERIVATIVES | DAISO CO., LTD. (JP) | 1999-07-14 | — | — | EP | disclosed |