Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6852995 | 0.89 | KEAP1 (0.47) | KEAP1NFE2L2ARLMNASMN1; SMN2 | |
| SCHEMBL6854181 | 0.83 | MAOB (0.48) | KEAP1NFE2L2ARLMNASMN1; SMN2 | |
| SCHEMBL6849377 | 0.82 | KEAP1 (0.40) | KEAP1NFE2L2ARLMNASMN1; SMN2 | |
| SCHEMBL6849586 | 0.81 | OPRK1 (0.42) | KEAP1NFE2L2ARLMNASMN1; SMN2 | |
| SCHEMBL6936062 | 0.81 | KEAP1 (0.40) | KEAP1NFE2L2ARLMNASMN1; SMN2 | |
| SCHEMBL6856861 | 0.77 | THRB (0.51) | KEAP1NFE2L2 | |
| SCHEMBL6852831 | 0.75 | KEAP1 (0.36) | KEAP1NFE2L2ARLMNASMN1; SMN2 | |
| SCHEMBL7751043 | 0.74 | HTR6 (0.49) | LMNASMN1; SMN2CA12CA1CA2 | |
| SCHEMBL7752409 | 0.74 | CA12 (0.60) | ARLMNASMN1; SMN2CA12CA1 | |
| SCHEMBL17962403 | 0.74 | ALDH1A1 (0.53) | ARLMNASMN1; SMN2HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030105078-A1 | Diphenyl derivatives | BAYER AKTIENGESSELLSCHAFT (DE) | 2003-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105078-A1 | Diphenyl derivatives | DPP4, DPP3, DPM1 | KEAP1 1863/4885NFE2L2 78/4885AR 1487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.