Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 2/20 | 0.56 |
| ▸ | TAS2R14 | Q9NYV8 | 4/20 | 0.56 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.56 |
| ▸ | PTGES | O14684 | 1/20 | 0.56 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 3/20 | 0.49 |
| ▸ | MMP9 | P14780 | 3/20 | 0.49 |
| ▸ | MMP13 | P45452 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8843349 | 0.87 | BMP1 (0.58) | BMP1TAS2R14CXCR3PTGESTAS2R8 | |
| SCHEMBL4797683 | 0.84 | BMP1 (0.55) | BMP1TAS2R14CXCR3PTGESTAS2R8 | |
| SCHEMBL7087595 | 0.84 | BMP1 (0.53) | BMP1TAS2R14CXCR3PTGESTAS2R8 | |
| SCHEMBL22265923 | 0.75 | ALDH1A1 (0.66) | BMP1TAS2R14CXCR3PTGESTAS2R8 | |
| SCHEMBL28729777 | 0.75 | TAS2R14 (0.80) | BMP1TAS2R14CXCR3PTGESTAS2R8 | |
| SCHEMBL7338644 | 0.75 | MEP1B (0.81) | BMP1TAS2R14CXCR3PTGESTAS2R8 | |
| SCHEMBL7343981 | 0.74 | BMP1 (0.77) | BMP1TAS2R14CXCR3PTGESTAS2R8 | |
| SCHEMBL5092519 | 0.74 | KEAP1 (0.81) | BMP1TAS2R14CXCR3PTGESTAS2R8 | |
| SCHEMBL6324095 | 0.74 | TAS2R14 (0.65) | BMP1TAS2R14CXCR3PTGESTAS2R8 | |
| Hydrochloric Acid SCHEMBL6379953 | 0.73 | MMP9 (0.57) | CXCR3ALDH1A1MMP1MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891328-B1 | PEPTIDYL COMPOUNDS HAVING MMP AND TNF INHIBITORY ACTIVITY | DARWIN DISCOVERY LTD (GB) | 2003-08-13 | — | — | EP | claimed |
| EP-0891328-B1 | PEPTIDYL COMPOUNDS HAVING MMP AND TNF INHIBITORY ACTIVITY | DARWIN DISCOVERY LTD (GB) | 2003-08-13 | — | — | EP | disclosed |