Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8473466 | 0.63 | ALOX12 (0.41) | NPC1RAB9AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL3077812 | 0.60 | CTSV (0.38) | GAAALDH1A1SMN1; SMN2CHRNA7HTR3A | |
| SCHEMBL1828600 | 0.59 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL7171239 | 0.58 | LTA4H (0.43) | MEN1KMT2A | |
| SCHEMBL4101527 | 0.58 | SPHK2 (0.47) | CHRNA7FFAR1MEN1KMT2A | |
| SCHEMBL7016053 | 0.58 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2LMNAFFAR1HTT | |
| SCHEMBL3072909 | 0.58 | CTSV (0.39) | GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL4101521 | 0.58 | SPHK2 (0.47) | CHRNA7FFAR1MEN1KMT2A | |
| SCHEMBL2244976 | 0.58 | USP30 (0.50) | SMN1; SMN2CHRM2CHRM3 | |
| SCHEMBL11875407 | 0.58 | NAAA (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030219883-A1 | Process for preparing optically active 3-hydroxypyrrolidine derivatives by enzymatic hydroxylation | LI ZHI (CH) | 2003-11-27 | — | — | US | disclosed |