Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | GOT1 | P17174 | 11/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7095695 | 0.82 | GAA (0.53) | GAAMAPTRECQLGOT1P2RX7 | |
| SCHEMBL7093710 | 0.80 | GAA (0.51) | GAAMAPTP2RX7HTR1ADRD2 | |
| SCHEMBL4378283 | 0.74 | ALDH1A1 (0.52) | GAAMAPT | |
| SCHEMBL2228008 | 0.71 | GOT1 (0.70) | GAAMAPTRECQLGOT1DRD2 | |
| SCHEMBL4377596 | 0.70 | USP2 (0.51) | MAPT | |
| SCHEMBL4378505 | 0.70 | NPC1 (0.57) | GAAMAPT | |
| SCHEMBL13636196 | 0.70 | MAPT (0.42) | MAPT | |
| SCHEMBL4378548 | 0.70 | USP2 (0.52) | MAPT | |
| SCHEMBL13933664 | 0.69 | GAA (0.74) | GAAMAPTRECQLGOT1 | |
| SCHEMBL7595099 | 0.69 | GAA (0.42) | GAAMAPTP2RX7HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030050307-A1 | Novel indole derivatives | H. LUNDBECK A/S (DK) | 2003-03-13 | — | — | US | disclosed |
| EP-1246818-A1 | NOVEL INDOLE DERIVATIVES | H. LUNDBECK A/S (DK) | 2002-10-09 | — | — | EP | disclosed |
| WO-2001049680-A1 | NOVEL INDOLE DERIVATIVES | H. LUNDBECK A/S (DK) | 2001-07-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030050307-A1 | Novel indole derivatives | HTR1A, HTR3C, HTR2C | GAA 4874/4885MAPT 3433/4885RECQL 3714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.