Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 11/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | IDH2 | P48735 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7092878 | 0.84 | KIF11 (0.46) | KIF11KDM4EIDH2LMNAMAPT | |
| SCHEMBL27529569 | 0.81 | CCR2 (0.52) | KDM4ELMNAMAPT | |
| Hydrochloric Acid SCHEMBL8650953 | 0.68 | MAPT (0.33) | KDM4ELMNAMAPT | |
| SCHEMBL1921482 | 0.68 | KIF11 (0.70) | KIF11IDH2MAPT | |
| SCHEMBL394991 | 0.68 | KIF11 (0.70) | KIF11KDM4EIDH2LMNAMAPT | |
| SCHEMBL20571662 | 0.67 | KCNH2 (0.36) | KDM4ELMNAMAPT | |
| SCHEMBL9765217 | 0.65 | KDM4E (0.51) | KDM4ELMNAMAPT | |
| SCHEMBL16411339 | 0.64 | KIF11 (0.65) | KIF11KDM4EIDH2MAPT | |
| SCHEMBL8388841 | 0.64 | SIGMAR1 (0.52) | KDM4EMAPT | |
| SCHEMBL1921505 | 0.64 | KIF11 (0.64) | KIF11IDH2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363897-A2 | ANTAGONISTS OF MCP-1 FUNCTION AND METHODS OF USE THEREOF | TELIK, INC. (US) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002070509-A2 | ANTAGONISTS OF MCP-1 FUNCTION AND METHODS OF USE THEREOF | TELIK, INC. (US) | 2002-09-12 | — | — | WO | disclosed |