SCHEMBL709106

SCHEMBL709106

Cc1ccccc1C(=O)ON(C)C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.51
MEN1 O00255 5/20 0.51
LMNA P02545 1/20 0.47
MAPT P10636 1/20 0.47
NPC1 O15118 3/20 0.47
RAB9A P51151 2/20 0.47
ESR1 P03372 1/20 0.45
ESR2 Q92731 1/20 0.45
TSHR P16473 1/20 0.44
UTS2R Q9UKP6 1/20 0.43
PLK1 P53350 1/20 0.43
PLK2 Q9NYY3 1/20 0.43
CASP3 P42574 1/20 0.43
SENP8 Q96LD8 1/20 0.43
SENP7 Q9BQF6 1/20 0.43
SENP6 Q9GZR1 1/20 0.43
HPGD P15428 1/20 0.43
ADRB2 P07550 2/20 0.42
ADRB1 P08588 2/20 0.42
ADRB3 P13945 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27903557 0.87 TSHR (0.50) KMT2ALMNAMAPTNPC1TSHR
SCHEMBL9315635 0.80 LMNA (0.62) KMT2AMEN1LMNAMAPTNPC1
SCHEMBL27460841 0.80 ALDH1A1 (0.56) LMNAMAPTESR1TSHRHPGD
SCHEMBL28189905 0.79 TSHR (0.48) KMT2AMEN1LMNAMAPTNPC1
SCHEMBL26598423 0.79 TSHR (0.75) KMT2AMEN1LMNATSHRL3MBTL1
SCHEMBL777261 0.79 NPC1 (0.53) KMT2AMEN1LMNAMAPTNPC1
SCHEMBL29436920 0.79 NPC1 (0.53) KMT2AMEN1LMNAMAPTNPC1
SCHEMBL127127 0.79 NPC1 (0.53) KMT2AMEN1LMNAMAPTNPC1
SCHEMBL19136737 0.78 ALDH1A1 (0.63) KMT2AMEN1MAPTNPC1RAB9A
SCHEMBL27274292 0.78 ALDH1A1 (0.45) KMT2AMEN1LMNAMAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2700698-B1 LIQUID CRYSTAL COMPOSITION LG CHEMICAL LTD (KR) 2020-03-25 EP disclosed
CN-110396374-A A kind of lithium battery case protective glue band and preparation method thereof and application method SUZHOU SAIWU APPLICATION TECH CO LTD 2019-11-01 CN disclosed
CN-105968822-B Heat-conducting silicon rubber and preparation method thereof, laser projection device 海信集团有限公司 2019-03-01 CN disclosed
CN-104395960-B Novel photoinitiator for photopolymer 科思创德国股份有限公司 2019-01-08 CN disclosed
US-9920249-B2 Liquid crystal composition LG CHEM, LTD. (KR) 2018-03-20 US disclosed
CN-106117921-B Heat conduction fluorubber and preparation method thereof, laser projection device 海信集团有限公司 2018-02-13 CN disclosed
CN-104540685-B Secure file and/or valuable document containing the viewable window with hologram 科思创德国股份有限公司 2017-09-26 CN disclosed
CN-104736349-B Polycarbonate-based security and/or value document having a hologram in the card body 科思创德国股份有限公司 2017-04-05 CN disclosed
CN-106117921-A Heat conduction fluorubber and preparation method thereof, laser projection device 海信集团有限公司 2016-11-16 CN disclosed
CN-105122368-A Protective lacquers and adhesives based on acrylate BAYER MATERIALSCIENCE AG 2015-12-02 CN disclosed
US-20100059712-A1 FLUORENE DERIVATIVE, LIQUID CRYSTAL COMPOSITION COMPRISING THE SAME, AND OPTICAL FILM USING THE SAME LIQUID CRYSTAL COMPOSITION LG CHEM, LTD. (KR) 2010-03-11 US disclosed
US-20100051867-A1 NOVEL LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION COMPRISING THE SAME, AND OPTICAL FILM USING THE SAME LIQUID CRYSTAL COMPOSITION LG CHEM, LTD. (KR) 2010-03-04 US disclosed
CN-101541784-A Hepatitis C virus inhibitors BRISTOL MYERS SQUIBB CO (US) 2009-09-23 CN disclosed
WO-2008091089-A1 NOVEL LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION COMPRISING THE SAME, AND OPTICAL FILM USING THE SAME LIQUID CRYSTAL COMPOSITION LG CHEM, LTD. (KR) 2008-07-31 WO disclosed
WO-2008091090-A1 NOVEL LIQUID CRYSTAL COMPOUND CONTAINING SULFONE GROUP, LIQUID CRYSTAL COMPOSITION COMPRISING THE SAME, AND OPTICAL FILM USING THE SAME LIQUID CRYSTAL COMPOSITION LG CHEM, LTD. (KR) 2008-07-31 WO disclosed
WO-2008091096-A1 FLUORENE DERIVATIVE, LIQUID CRYSTAL COMPOSITION COMPRISING THE SAME, AND OPTICAL FILM USING THE SAME LIQUID CRYSTAL COMPOSITION LG CHEM, LTD. (KR) 2008-07-31 WO disclosed
WO-2008091088-A1 DISCOTIC LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION COMPRISING THE SAME AND OPTICAL FILM USING THE SAME LIQUID CRYSTAL COMPOSITION LG CHEM, LTD. (KR) 2008-07-31 WO disclosed
WO-2008091092-A1 BIAXIAL LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION COMPRISING THE SAME, AND OPTICAL FILM USING THE SAME LIQUID CRYSTAL COMPOSITION LG CHEM, LTD. (KR) 2008-07-31 WO disclosed
CN-101024671-A Hepatitis C virus inhibitors BRISTOL MYERS SQUIBB CO (US) 2007-08-29 CN disclosed
CN-1974596-A Hepatitis C virus inhibitors BRISTOL MYERS SQUIBB CO (US) 2007-06-06 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100059712-A1 FLUORENE DERIVATIVE, LIQUID CRYSTAL COMPOSITION COMPRISING THE SAME, AND OPTICAL FILM USING THE SAME LIQUID CRYSTAL COMPOSITION FLNA, FMNL1, CFAP20 KMT2A 2112/4885MEN1 977/4885LMNA 899/4885
US-20100051867-A1 NOVEL LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION COMPRISING THE SAME, AND OPTICAL FILM USING THE SAME LIQUID CRYSTAL COMPOSITION CRYAA, UACA, AUP1 KMT2A 2318/4885MEN1 1439/4885LMNA 1555/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.