Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.40 |
| ▸ | CA2 | P00918 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.37 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.37 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SIGLEC9 | Q9Y336 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7092239 | 0.90 | CA2 (0.48) | CA1CA2TPSAB1TPSD1TPSG1 | |
| SCHEMBL7091373 | 0.81 | GHSR (0.51) | MAPK1TPSAB1TPSD1TPSG1ADRB3 | |
| SCHEMBL7569340 | 0.81 | GHSR (0.51) | MAPK1TPSAB1TPSD1TPSG1ADRB3 | |
| SCHEMBL7091421 | 0.80 | CA12 (0.53) | CA1CA2ALDH1A1MAPK1TSHR | |
| SCHEMBL7179722 | 0.80 | CA1 (0.42) | CA1CA2TPSAB1TPSD1TPSG1 | |
| SCHEMBL7144484 | 0.78 | ALDH1A1 (0.51) | CA1CA2ALDH1A1MAPK1TSHR | |
| SCHEMBL7243806 | 0.77 | EPHX2 (0.47) | MAPK1ADRB3ADRB1NAMPT | |
| SCHEMBL7235601 | 0.77 | EPHX2 (0.47) | MAPK1ADRB3ADRB1NAMPT | |
| SCHEMBL7091709 | 0.74 | ADRB3 (0.59) | CA1CA2ALDH1A1MAPK1TPSAB1 | |
| SCHEMBL7092200 | 0.74 | ALDH1A1 (0.47) | ALDH1A1MAPK1TSHRNAMPTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030018045-A1 | Heterocyclic beta-3 adrenergic receptor agonists | WYETH (US) | 2003-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030018045-A1 | Heterocyclic beta-3 adrenergic receptor agonists | ADRB2, ADRB1, ADRB3 | CA1 4874/4885CA2 2958/4885ALDH1A1 725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.