Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 10/20 | 0.48 |
| ▸ | CA1 | P00915 | 8/20 | 0.48 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.44 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.44 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.44 |
| ▸ | GHSR | Q92847 | 2/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 4/20 | 0.42 |
| ▸ | CA9 | Q16790 | 4/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7091444 | 0.90 | CA1 (0.40) | CA2CA1TPSAB1TPSD1TPSG1 | |
| SCHEMBL7091373 | 0.90 | GHSR (0.51) | TPSAB1TPSD1TPSG1GHSRADRB3 | |
| SCHEMBL7569340 | 0.90 | GHSR (0.51) | TPSAB1TPSD1TPSG1GHSRADRB3 | |
| SCHEMBL7179722 | 0.87 | CA1 (0.42) | CA2CA1TPSAB1TPSD1TPSG1 | |
| SCHEMBL7243806 | 0.83 | EPHX2 (0.47) | ADRB3ADRB1NAMPTMMP1MMP3 | |
| SCHEMBL7235601 | 0.83 | EPHX2 (0.47) | ADRB3ADRB1NAMPTMMP1MMP3 | |
| SCHEMBL7091709 | 0.83 | ADRB3 (0.59) | CA2CA1TPSAB1TPSD1TPSG1 | |
| SCHEMBL7092216 | 0.80 | ADRB3 (0.48) | CA2CA1TPSAB1TPSD1TPSG1 | |
| Formic Acid SCHEMBL7091936 | 0.76 | TPSAB1 (0.48) | CA2CA1TPSAB1TPSD1TPSG1 | |
| Formic Acid SCHEMBL7097100 | 0.75 | ADRB3 (0.55) | CA2CA1TPSAB1TPSD1TPSG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030018045-A1 | Heterocyclic beta-3 adrenergic receptor agonists | WYETH (US) | 2003-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030018045-A1 | Heterocyclic beta-3 adrenergic receptor agonists | ADRB2, ADRB1, ADRB3 | CA2 2958/4885CA1 4874/4885TPSAB1 596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.