Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 5/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7088438 | 0.82 | TRPA1 (0.32) | HTR1AALDH1A1POLB | |
| SCHEMBL6984266 | 0.76 | NPC1L1 (0.41) | CHRM2CHRM3ALDH1A1 | |
| SCHEMBL6982745 | 0.75 | NPC1L1 (0.39) | CHRM2CHRM3ALDH1A1 | |
| SCHEMBL14677078 | 0.69 | GRIN2B (0.34) | — | |
| SCHEMBL7091460 | 0.65 | F10 (0.47) | — | |
| SCHEMBL7090877 | 0.65 | SIGMAR1 (0.36) | HTR1ACHRM2CHRM3ALDH1A1POLB | |
| SCHEMBL28702537 | 0.63 | RXFP1 (0.34) | ALDH1A1RXFP1 | |
| SCHEMBL7084911 | 0.61 | GFER (0.46) | CHRM2CHRM3ALDH1A1POLB | |
| SCHEMBL27483341 | 0.60 | CYP2D6 (0.34) | — | |
| SCHEMBL27467938 | 0.60 | METAP2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294716-A1 | LACTAM INHIBITORS OF FACTOR XA AND METHOD | Bristol-Myers Squibb Company (US) | 2003-03-26 | — | — | EP | disclosed |
| WO-2001096331-A1 | LACTAM INHIBITORS OF FACTOR XA AND METHOD | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |