SCHEMBL709164

SCHEMBL709164

CSc1ccc(C(=O)C2(C)C[N]CCO2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
TSHR P16473 2/20 0.39
MAPK1 P28482 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
PLK1 P53350 1/20 0.38
FPR2 P25090 1/20 0.33
HAO1 Q9UJM8 1/20 0.33
LMNA P02545 3/20 0.32
TP53 P04637 1/20 0.32
POLB P06746 1/20 0.32
ADORA3 P0DMS8 1/20 0.32
MMP2 P08253 1/20 0.32
MMP9 P14780 1/20 0.32
MMP8 P22894 1/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
HPGD P15428 2/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
CASP3 P42574 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL709166 0.76 ALDH1A1 (0.38) ALDH1A1TSHRMAPK1SMN1; SMN2PLK1
SCHEMBL11988913 0.67 POLB (0.41) ALDH1A1TSHRMAPK1SMN1; SMN2PLK1
SCHEMBL12952156 0.66 PLK1 (0.44) ALDH1A1TSHRMAPK1SMN1; SMN2PLK1
SCHEMBL195321 0.64 HPGD (0.70) ALDH1A1TSHRMAPK1SMN1; SMN2PLK1
SCHEMBL6986662 0.64 PLK1 (0.46) ALDH1A1TSHRMAPK1SMN1; SMN2PLK1
SCHEMBL5859663 0.62 PLK1 (0.61) ALDH1A1TSHRSMN1; SMN2PLK1HAO1
SCHEMBL6182687 0.62 PLK1 (0.61) ALDH1A1TSHRSMN1; SMN2PLK1HAO1
SCHEMBL10885785 0.62 PLK1 (0.43) ALDH1A1TSHRMAPK1SMN1; SMN2PLK1
SCHEMBL726159 0.62 MEN1 (0.46) ALDH1A1TSHRMAPK1SMN1; SMN2PLK1
SCHEMBL20534343 0.61 PLK1 (0.55) ALDH1A1TSHRMAPK1SMN1; SMN2PLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118185222-A SBS-based dynamic reversible cross-linked luminous liquid crystal elastomer and preparation method thereof 大连理工大学 2024-06-14 CN claimed
CN-114957863-B Heat-conducting polypropylene modified material for ice making box of refrigerator, preparation method and ice making box of refrigerator and refrigerator comprising heat-conducting polypropylene modified material 海信冰箱有限公司 2024-05-28 CN claimed
CN-111138810-B UV patternable polymer blend for organic thin film transistor 康宁股份有限公司 2024-05-17 CN claimed
CN-117980348-A Compositions based on (meth) acrylate monomers 博斯蒂克股份公司 2024-05-03 CN claimed
CN-117355544-A Compositions based on (meth) acrylate monomers 博斯蒂克股份公司 2024-01-05 CN claimed
CN-113015610-B Hydrolytically stable polymers, method for synthesizing same, and use thereof in bioelectronic devices 德州系统大学董事会 2023-05-30 CN claimed
CN-118339697-A Battery comprising a high concentration electrolyte and a negative electrode having a metal substrate and a protective layer 尤米科尔公司 2024-07-12 CN disclosed
CN-118339674-A Negative electrode comprising a metal substrate and a protective layer 尤米科尔公司 2024-07-12 CN disclosed
CN-118302424-A Dielectric materials based on heteroaromatic extended bismaleimides 默克专利有限公司 2024-07-05 CN disclosed
CN-118284673-A Compositions based on (meth) acrylate monomers 博斯蒂克股份公司 2024-07-02 CN disclosed
CN-118284858-A Electrophotographic photoreceptor, electrophotographic photoreceptor cartridge, and image forming apparatus 三菱化学株式会社 2024-07-02 CN disclosed
CN-118215511-A GELMA polymer compositions and uses thereof 盖尔梅迪克斯公司 2024-06-18 CN disclosed
CN-118185222-A SBS-based dynamic reversible cross-linked luminous liquid crystal elastomer and preparation method thereof 大连理工大学 2024-06-14 CN disclosed
US-20100051867-A1 NOVEL LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION COMPRISING THE SAME, AND OPTICAL FILM USING THE SAME LIQUID CRYSTAL COMPOSITION LG CHEM, LTD. (KR) 2010-03-04 US disclosed
WO-2008143470-A2 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION AND OPTICAL FILM AND DEVICE USING THE SAME LG CHEM, LTD. (KR) 2008-11-27 WO disclosed
WO-2008091090-A1 NOVEL LIQUID CRYSTAL COMPOUND CONTAINING SULFONE GROUP, LIQUID CRYSTAL COMPOSITION COMPRISING THE SAME, AND OPTICAL FILM USING THE SAME LIQUID CRYSTAL COMPOSITION LG CHEM, LTD. (KR) 2008-07-31 WO disclosed
WO-2008091089-A1 NOVEL LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION COMPRISING THE SAME, AND OPTICAL FILM USING THE SAME LIQUID CRYSTAL COMPOSITION LG CHEM, LTD. (KR) 2008-07-31 WO disclosed
WO-2008091096-A1 FLUORENE DERIVATIVE, LIQUID CRYSTAL COMPOSITION COMPRISING THE SAME, AND OPTICAL FILM USING THE SAME LIQUID CRYSTAL COMPOSITION LG CHEM, LTD. (KR) 2008-07-31 WO disclosed
WO-2008091088-A1 DISCOTIC LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION COMPRISING THE SAME AND OPTICAL FILM USING THE SAME LIQUID CRYSTAL COMPOSITION LG CHEM, LTD. (KR) 2008-07-31 WO disclosed
WO-2008091092-A1 BIAXIAL LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION COMPRISING THE SAME, AND OPTICAL FILM USING THE SAME LIQUID CRYSTAL COMPOSITION LG CHEM, LTD. (KR) 2008-07-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100051867-A1 NOVEL LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION COMPRISING THE SAME, AND OPTICAL FILM USING THE SAME LIQUID CRYSTAL COMPOSITION CRYAA, UACA, AUP1 ALDH1A1 4650/4885TSHR 4346/4885MAPK1 2349/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.