Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7095190 | 0.83 | ALDH1A1 (0.35) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL7091813 | 0.78 | TAAR1 (0.39) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL7094091 | 0.77 | ALOX5 (0.37) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL6987711 | 0.74 | ALDH1A1 (0.38) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL7091836 | 0.73 | ALDH1A1 (0.38) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL6967654 | 0.73 | TAAR1 (0.44) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL23178803 | 0.71 | MAPT (0.41) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL83319 | 0.70 | NPC1 (0.46) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL29135509 | 0.69 | ALDH1A1 (0.46) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL24274929 | 0.69 | ALDH1A1 (0.40) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0970059-B1 | DISUBSTITUTED BIPHENYLOXAZOLINES | BAYER CROPSCIENCE AG (DE) | 2003-08-20 | — | — | EP | disclosed |
| US-20020086892-A1 | For controlling animal pests, in particular: insects, arachnids and nematodes | BAYER AKTIENGESELLSCHAFT (DE) | 2002-07-04 | — | — | US | disclosed |
| US-20020087001-A1 | Substituted piperidine derivatives | RAE DUNCAN ROBERTSON (GB) | 2002-07-04 | — | — | US | disclosed |
| US-6410581-B1 | INSECTICIDES, MITICIDES, NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-06-25 | — | — | US | disclosed |
| US-6365604-B1 | Antipsychotic substituted piperidine derivatives | AKZO NOBEL NV (NL) | 2002-04-02 | — | — | US | disclosed |
| EP-0970059-A1 | DISUBSTITUTED BIPHENYLOXAZOLINES | BAYER AG (DE) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998039310-A1 | DISUBSTITUTED BIPHENYLOXAZOLINES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-09-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020086892-A1 | For controlling animal pests, in particular: insects, arachnids and nematodes | ATXN2, HAX1, ANTXR2 | ALDH1A1 1608/4885NPC1 3730/4885RAB9A 1115/4885 |
| US-20020087001-A1 | Substituted piperidine derivatives | DRD2, GRIN2C, DRD4 | ALDH1A1 886/4885NPC1 563/4885RAB9A 1369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.