Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1116034 | 0.83 | CYP3A4 (0.58) | ALDH1A1CYP1A2CYP2D6CYP2C19TSHR | |
| SCHEMBL7369209 | 0.83 | ALDH1A1 (0.46) | ALDH1A1CYP1A2CYP2C19KMT2ATSHR | |
| SCHEMBL1952775 | 0.82 | ALDH1A1 (0.64) | ALDH1A1CYP1A2CYP2D6CYP2C19KMT2A | |
| SCHEMBL40266 | 0.79 | PKM (0.46) | ALDH1A1CYP1A2CYP2D6CYP2C19KMT2A | |
| SCHEMBL10661895 | 0.77 | ALDH1A1 (0.47) | ALDH1A1CYP1A2CYP2D6CYP2C19KMT2A | |
| SCHEMBL8773146 | 0.77 | TSHR (0.51) | ALDH1A1CYP1A2CYP2D6CYP2C19KMT2A | |
| SCHEMBL6121980 | 0.74 | ALDH1A1 (0.47) | ALDH1A1KMT2ATSHRCYP3A4ALOX15 | |
| SCHEMBL11316296 | 0.74 | PKM (0.50) | ALDH1A1CYP1A2CYP2D6CYP2C19KMT2A | |
| SCHEMBL11310440 | 0.74 | PKM (0.50) | ALDH1A1CYP1A2CYP2D6CYP2C19KMT2A | |
| SCHEMBL505380 | 0.72 | ALDH1A1 (0.50) | ALDH1A1CYP1A2CYP2D6CYP2C19TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6617330-B2 | For controlling and preventing pests | SYNGENTA PARTICIPATIONS AG (CH) | 2003-09-09 | — | — | US | disclosed |
| US-20030040521-A1 | Novel pyrimidin-4-enamine as fungicide | SYNGENTA PARTICIPATIONS AG (CH) | 2003-02-27 | — | — | US | disclosed |
| EP-1124830-A1 | PYRIMIDIN-4-ENAMINE AS FUNGICIDE | Syngenta Participations AG (CH) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000031082-A1 | PYRIMIDIN-4-ENAMINE AS FUNGICIDE | SYNGENTA PARTICIPATIONS AG (CH) | 2000-06-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030040521-A1 | Novel pyrimidin-4-enamine as fungicide | AOC1, CBR3, AOC3 | ALDH1A1 1176/4885CYP1A2 429/4885CYP2D6 82/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.