Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NQO2 | P16083 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenazine SCHEMBL2873102 | 0.85 | MAPT (0.50) | MAPTNQO2ALDH1A1POLBSMN1; SMN2 | |
| Phenazine SCHEMBL94396 | 0.85 | MAPT (0.50) | MAPTNQO2ALDH1A1POLBSMN1; SMN2 | |
| Phenazine SCHEMBL10876543 | 0.85 | MAPT (0.50) | MAPTNQO2ALDH1A1POLBSMN1; SMN2 | |
| Phenazine SCHEMBL22631548 | 0.81 | MAPT (0.55) | MAPTNQO2ALDH1A1POLBSMN1; SMN2 | |
| Phenazine SCHEMBL1750964 | 0.78 | MAPT (0.58) | MAPTNQO2ALDH1A1POLBSMN1; SMN2 | |
| Phenazine SCHEMBL2923781 | 0.78 | MAPT (0.65) | MAPTNQO2ALDH1A1POLBSMN1; SMN2 | |
| Phenazine SCHEMBL8564741 | 0.78 | MAPT (0.65) | MAPTNQO2ALDH1A1POLBSMN1; SMN2 | |
| Phenazine SCHEMBL28658053 | 0.76 | MAPT (0.55) | MAPTNQO2ALDH1A1POLBSMN1; SMN2 | |
| Phenazine SCHEMBL28835271 | 0.75 | MAPT (0.61) | MAPTNQO2ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL130487 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003082187-A2 | PURIFICATION AND CLONING OF NMN ADENYLYLTRANSERASE AND ITS THERAPEUTIC USE | INDIANA UNIVERSITY (US) | 2003-10-09 | — | — | WO | disclosed |