Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 16/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9351736 | 0.78 | KEAP1 (0.65) | KDM4EMEN1MAPTRAB9AKMT2A | |
| SCHEMBL16187949 | 0.78 | KMT2A (0.60) | MEN1MAPTKMT2ATRPV1RECQL | |
| SCHEMBL808090 | 0.77 | HKDC1 (0.61) | MEN1MAPTKMT2ATRPV1RECQL | |
| SCHEMBL4649512 | 0.75 | TRPV1 (0.50) | KDM4EMEN1MAPTRAB9AKMT2A | |
| SCHEMBL11019096 | 0.75 | TRPV1 (0.49) | KDM4EMEN1MAPTRAB9AKMT2A | |
| SCHEMBL1413142 | 0.74 | MCL1 (0.50) | KDM4EMEN1MAPTRAB9AKMT2A | |
| SCHEMBL808375 | 0.74 | HSD17B2 (0.64) | CA1CA2RECQL | |
| SCHEMBL11414744 | 0.74 | NFKBIA (0.56) | KDM4EMEN1MAPTKMT2ATRPV1 | |
| SCHEMBL16187950 | 0.74 | MEN1 (0.58) | KDM4EMEN1MAPTRAB9AKMT2A | |
| SCHEMBL6087112 | 0.73 | CA1 (0.63) | KDM4EMEN1KMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0896533-A4 | PENTAFLUOROBENZENESULFONAMIDES AND ANALOGS | TULARIK INC (US) | 1999-04-28 | — | — | EP | claimed |
| EP-0896533-A2 | PENTAFLUOROBENZENESULFONAMIDES AND ANALOGS | TULARIK, INC. (US) | 1999-02-17 | — | — | EP | claimed |
| WO-1997030677-A2 | PENTAFLUOROBENZENESULFONAMIDES AND ANALOGS | TULARIK, INC. (US) | 1997-08-28 | — | — | WO | claimed |
| EP-0896533-B1 | PENTAFLUOROBENZENESULFONAMIDES AND ANALOGS | TULARIK INC (US) | 2003-09-10 | — | — | EP | disclosed |
| EP-1334719-A2 | Pentafluorobenzenesulfonamides and analogs | TULARIK, INC. (US) | 2003-08-13 | — | — | EP | disclosed |
| EP-0896533-A4 | PENTAFLUOROBENZENESULFONAMIDES AND ANALOGS | TULARIK INC (US) | 1999-04-28 | — | — | EP | disclosed |
| EP-0896533-A2 | PENTAFLUOROBENZENESULFONAMIDES AND ANALOGS | TULARIK, INC. (US) | 1999-02-17 | — | — | EP | disclosed |
| WO-1997030677-A2 | PENTAFLUOROBENZENESULFONAMIDES AND ANALOGS | TULARIK, INC. (US) | 1997-08-28 | — | — | WO | disclosed |