Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1828600 | 0.77 | ALDH1A1 (0.39) | CYP1A2MEN1KMT2AALOX5KDM4E | |
| SCHEMBL5871698 | 0.76 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL8473466 | 0.70 | ALOX12 (0.41) | MEN1KMT2ATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL7092607 | 0.67 | — | — | |
| SCHEMBL11841829 | 0.66 | CYP1A2 (0.41) | CYP1A2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7090597 | 0.66 | NPC1 (0.35) | MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL1829382 | 0.62 | LTA4H (0.39) | MEN1KMT2ATSHRKDM4EALDH1A1 | |
| SCHEMBL1827943 | 0.62 | LTA4H (0.40) | CYP1A2TSHRKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL14156263 | 0.62 | SMN1; SMN2 (0.46) | MEN1KMT2ATSHRKDM4EALDH1A1 | |
| SCHEMBL7171239 | 0.61 | LTA4H (0.43) | MEN1KMT2ATSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030219883-A1 | Process for preparing optically active 3-hydroxypyrrolidine derivatives by enzymatic hydroxylation | LI ZHI (CH) | 2003-11-27 | — | — | US | disclosed |