Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1286296 | 0.81 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL6947156 | 0.79 | CASP1 (0.53) | ALDH1A1CASP1 | |
| SCHEMBL2102326 | 0.78 | HTR1A (0.43) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL9084422 | 0.76 | CASP1 (0.36) | ALDH1A1CASP1 | |
| SCHEMBL15592597 | 0.76 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL9506098 | 0.74 | L3MBTL1 (0.53) | ALDH1A1CASP1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1750320 | 0.74 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL7448545 | 0.74 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL28516086 | 0.73 | L3MBTL1 (0.55) | ALDH1A1CASP1SMN1; SMN2 | |
| SCHEMBL9082309 | 0.73 | LTA4H (0.38) | ALDH1A1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7141412-B2 | Process for preparing optically active 3-hydroxypyrrolidine derivatives by enzymatic hydroxylation | EIDGENOSSISCHE TECHNISCHE HOCHSCHULE ZURICH (CH) | 2006-11-28 | — | — | US | disclosed |
| EP-1131460-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE 3-HYDROXY-PYRROLIDINE DERIVATIVEES BY ENZYMATIC HYDROXYLATION | Eidgenössische Technische Hochschule Zürich (CH) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000029606-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE-3-HYDROXY-PYRROLIDINE DERIVATIVES BY ENZYMATIC HYDROXYLATION | Eidgenössische Technische Hochschule Zürich (CH) | 2000-05-25 | — | — | WO | disclosed |