Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 6/20 | 0.52 |
| ▸ | RORC | P51449 | 5/20 | 0.52 |
| ▸ | THRA | P10827 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7094647 | 0.87 | THRB (0.61) | THRBRORCTHRA | |
| SCHEMBL8799780 | 0.86 | RORC (0.68) | THRBRORCTHRA | |
| SCHEMBL282551 | 0.79 | THRB (0.55) | THRBRORCTHRA | |
| SCHEMBL7097286 | 0.78 | THRB (0.75) | THRBRORCTHRA | |
| SCHEMBL8799875 | 0.77 | THRB (0.60) | THRBRORCTHRA | |
| SCHEMBL7151397 | 0.77 | THRB (0.77) | THRBTHRA | |
| SCHEMBL22959176 | 0.74 | RORC (0.70) | THRBRORCTHRA | |
| SCHEMBL22959162 | 0.74 | RORC (0.70) | THRBRORCTHRA | |
| SCHEMBL8799433 | 0.74 | THRA (0.80) | THRBTHRA | |
| SCHEMBL5618338 | 0.74 | THRB (0.56) | THRBRORCTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030166731-A1 | Method of treating hair loss using diphenylether derivatives | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 2003-09-04 | — | — | US | disclosed |
| US-6525094-B1 | Topical application of compound that interacts strongly with thyroid hormone receptors but sparingly with heart selective hormone receptors | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 2003-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030166731-A1 | Method of treating hair loss using diphenylether derivatives | CYP27A1, DHCR7, CYP11A1 | THRB 716/4885RORC 1125/4885THRA 1397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.