Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | TRPM2 | O94759 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL812401 | 0.80 | PGR (0.40) | ESR2SMN1; SMN2ALDH1A1HTTGAA | |
| SCHEMBL8650400 | 0.72 | GAA (0.54) | KDM4ESMN1; SMN2ALDH1A1HTTGAA | |
| SCHEMBL7098248 | 0.72 | ELANE (0.36) | KDM4ESMN1; SMN2ALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL7098246 | 0.70 | ALDH1A1 (0.38) | ALDH1A1GAAMEN1LMNAKMT2A | |
| SCHEMBL20779245 | 0.67 | ESR2 (0.48) | ESR2DHFRCYP1A2LMNAHPGD | |
| SCHEMBL5771881 | 0.65 | MAPT (0.33) | KDM4EALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL812402 | 0.64 | PGR (0.49) | MAOBALDH1A1HPGD | |
| SCHEMBL13176917 | 0.63 | ESR2 (0.48) | ESR2DHFRCYP1A1CYP1A2LMNA | |
| SCHEMBL4830408 | 0.62 | ESR2 (0.60) | ESR2PDE3BPDE3APDE4APDE4B | |
| SCHEMBL6207998 | 0.61 | ALDH1A1 (0.49) | KDM4ESMN1; SMN2ALDH1A1GAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030096806-A1 | Arylphenyl-substituted cyclic ketoenols | LIEB FOLKER (DE) | 2003-05-22 | — | — | US | disclosed |
| US-6451843-B1 | Arylphenyl-substituted cyclic keto enols | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-17 | — | — | US | disclosed |
| EP-1075465-A1 | ARYLPHENYL-SUBSTITUTED CYCLIC KETO ENOLS | BAYER AG (DE) | 2001-02-14 | — | — | EP | disclosed |
| WO-1999055673-A1 | ARYLPHENYL-SUBSTITUTED CYCLIC KETO ENOLS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030096806-A1 | Arylphenyl-substituted cyclic ketoenols | KCNE1, KCNQ3, SULT1E1 | ESR2 1499/4885PDE3B 2145/4885PDE3A 2103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.