Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.32 |
| ▸ | ROS1 | P08922 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL812403 | 0.86 | SMN1; SMN2 (0.43) | ALDH1A1HPGDKMT2AHSD17B10KDM4E | |
| SCHEMBL6207995 | 0.72 | PGR (0.40) | ALDH1A1HPGDKMT2AHSD17B10KDM4E | |
| SCHEMBL7098243 | 0.72 | ESR2 (0.35) | ALDH1A1HPGDKMT2AHSD17B10KDM4E | |
| SCHEMBL812401 | 0.69 | PGR (0.40) | ALDH1A1SMN1; SMN2TNKS2PTGESMAPT | |
| SCHEMBL8650400 | 0.69 | GAA (0.54) | ALDH1A1HPGDKMT2AHSD17B10KDM4E | |
| SCHEMBL6989515 | 0.69 | ACHE (0.41) | ALDH1A1KMT2AKDM4ETSHRMEN1 | |
| SCHEMBL13176930 | 0.68 | PLA2G7 (0.50) | ELANEALDH1A1HPGDKMT2ANPC1 | |
| SCHEMBL5771881 | 0.65 | MAPT (0.33) | ALDH1A1HPGDKMT2AKDM4EPBRM1 | |
| SCHEMBL6838459 | 0.65 | PBRM1 (0.39) | ALDH1A1PBRM1MAPT | |
| SCHEMBL29354513 | 0.63 | ELANE (0.42) | ELANEALDH1A1HPGDKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030096806-A1 | Arylphenyl-substituted cyclic ketoenols | LIEB FOLKER (DE) | 2003-05-22 | — | — | US | disclosed |
| US-6451843-B1 | Arylphenyl-substituted cyclic keto enols | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030096806-A1 | Arylphenyl-substituted cyclic ketoenols | KCNE1, KCNQ3, SULT1E1 | ELANE 1517/4885ALDH1A1 1961/4885HPGD 511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.