Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 4/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 2/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7100804 | 0.85 | HPGD (0.40) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL7100866 | 0.77 | HPGD (0.48) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL11028392 | 0.75 | MME (0.40) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL7097121 | 0.75 | TLR2 (0.42) | ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL27530431 | 0.74 | CTSB (0.44) | ALDH1A1MEN1KMT2ACTSBCTSS | |
| SCHEMBL10694799 | 0.74 | LAP3 (0.44) | ALDH1A1HPGDCTSB | |
| SCHEMBL27744904 | 0.71 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2ACTSB | |
| SCHEMBL16166282 | 0.71 | SLC1A3 (0.41) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL5447568 | 0.70 | KMT2A (0.54) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL6298147 | 0.70 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815084-B1 | LACTAM-CONTAINING HYDROXAMIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEASE | PROCTER & GAMBLE (US) | 2003-08-27 | — | — | EP | disclosed |
| US-5672598-A | MATRIX METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1997-09-30 | — | — | US | disclosed |