Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7098517 | 0.89 | ALDH1A1 (0.40) | ALDH1A1NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL4430185 | 0.84 | NPC1 (0.44) | ALDH1A1NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL7097844 | 0.84 | LTA4H (0.44) | ALDH1A1NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL30111341 | 0.80 | LMNA (0.41) | ALDH1A1NPC1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL473811 | 0.80 | LMNA (0.41) | ALDH1A1NPC1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL20357876 | 0.80 | CYP3A4 (0.47) | ALDH1A1CYP3A4CA2LMNAHSD17B10 | |
| SCHEMBL17212283 | 0.80 | NPC1 (0.40) | ALDH1A1NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL28344806 | 0.80 | LMNA (0.39) | ALDH1A1CYP3A4CA2LMNATSHR | |
| SCHEMBL18979221 | 0.79 | LMNA (0.40) | ALDH1A1KDM4ECYP3A4CA2LMNA | |
| SCHEMBL17831410 | 0.79 | LMNA (0.39) | ALDH1A1NPC1RAB9AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760111-A | TEXTILE STABILIZERS WITH PHOTOSTABILIZERS, OXIDATION OR HEAT RESISTANCE | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-06-02 | — | — | US | disclosed |
| US-5688995-A | SUNSCREEN AGENTS | CIBA-GEIGY CORPORATION (US) | 1997-11-18 | — | — | US | disclosed |