SCHEMBL7099261

SCHEMBL7099261

CCc1ccc(C(=O)C2=C(c3ccccc3)C(=O)c3ccccc3C2=O)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.73
ALDH1A1 P00352 6/20 0.73
SMN1; SMN2 Q16637 5/20 0.73
NPSR1 Q6W5P4 5/20 0.73
MEN1 O00255 4/20 0.73
KMT2A Q03164 4/20 0.73
L3MBTL1 Q9Y468 3/20 0.73
HKDC1 Q2TB90 2/20 0.73
XBP1 P17861 2/20 0.73
HSP90AA1 P07900 5/20 0.57
HSP90AB1 P08238 3/20 0.57
FGFR1 P11362 6/20 0.50
FGFR2 P21802 6/20 0.50
FGFR4 P22455 6/20 0.50
FGFR3 P22607 6/20 0.50
SRC P12931 3/20 0.50
PTPN1 P18031 1/20 0.49
MAPT P10636 6/20 0.48
HTT P42858 4/20 0.48
TDP1 Q9NUW8 4/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17969761 0.96 LMNA (0.66) LMNAALDH1A1SMN1; SMN2NPSR1MEN1
SCHEMBL17969764 0.94 LMNA (0.73) LMNAALDH1A1SMN1; SMN2NPSR1MEN1
SCHEMBL17969759 0.91 MEN1 (0.59) LMNAALDH1A1SMN1; SMN2NPSR1MEN1
SCHEMBL5390429 0.85 ALDH1A1 (1.00) LMNAALDH1A1SMN1; SMN2NPSR1MEN1
SCHEMBL21470360 0.81 MEN1 (0.79) LMNAALDH1A1SMN1; SMN2NPSR1MEN1
SCHEMBL17969760 0.81 NPSR1 (0.58) LMNAALDH1A1SMN1; SMN2NPSR1MEN1
SCHEMBL30885094 0.80 LMNA (0.88) LMNAALDH1A1SMN1; SMN2NPSR1MEN1
SCHEMBL17969757 0.80 MEN1 (0.71) LMNAALDH1A1SMN1; SMN2NPSR1MEN1
SCHEMBL17969765 0.78 MEN1 (0.79) LMNAALDH1A1SMN1; SMN2NPSR1MEN1
SCHEMBL8018163 0.77 LMNA (0.71) LMNAALDH1A1SMN1; SMN2NPSR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220128913-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2022-04-28 US disclosed
EP-0764886-B1 Electrophotosensitive material containing a naphthoquinone derivative KYOCERA MITA CORP (JP) 2003-09-03 EP disclosed
US-5994012-A CHARGE GENERATING COMPOUND, CHARGE TRANSFER COMPOUND AND BINDER MITA INDUSTRIAL CO., LTD. (JP) 1999-11-30 US disclosed
US-5863688-A REACTING 1,3-INDANDIONE DERIVATIVE WITH A BROMOACETIC ESTER TO FORM 1,3-INDANDIONE ESTER, ISOMERIZING THE ESTER DERIVATIVE IN PRESENCE OF SODIUM HYDRIDE TO FORM NAPHTHOIC ESTER, OXIDIZING TO FORM NAPHTHOQUINONE DERIVATIVE MITA INDUSTRIAL CO., LTD (JP) 1999-01-26 US disclosed
EP-0764886-A2 Naphthoquinone derivative and electrophotosensitive material using the same MITA INDUSTRIAL CO. LTD. (JP) 1997-03-26 EP disclosed