SCHEMBL17969764

SCHEMBL17969764

CCc1ccc(C2=C(C(=O)c3ccccc3)C(=O)c3ccccc3C2=O)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 5/20 0.73
▸ SMN1; SMN2 Q16637 5/20 0.73
▸ MEN1 O00255 4/20 0.73
▸ KMT2A Q03164 4/20 0.73
▸ NPSR1 Q6W5P4 4/20 0.73
▸ ALDH1A1 P00352 4/20 0.73
▸ L3MBTL1 Q9Y468 3/20 0.73
▸ HKDC1 Q2TB90 2/20 0.73
▸ XBP1 P17861 2/20 0.73
▸ HSP90AA1 P07900 7/20 0.54
▸ HSP90AB1 P08238 5/20 0.54
▸ MAPT P10636 4/20 0.51
▸ NPC1 O15118 3/20 0.51
▸ MAPK1 P28482 3/20 0.51
▸ RAB9A P51151 3/20 0.51
▸ HTT P42858 3/20 0.51
▸ TDP1 Q9NUW8 3/20 0.51
▸ KDM4E B2RXH2 2/20 0.51
▸ MPI P34949 2/20 0.51
▸ TP53 P04637 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17969761 0.96 LMNA (0.66) LMNASMN1; SMN2MEN1KMT2ANPSR1
SCHEMBL7099261 0.94 LMNA (0.73) LMNASMN1; SMN2MEN1KMT2ANPSR1
SCHEMBL17969759 0.91 MEN1 (0.59) LMNASMN1; SMN2MEN1KMT2ANPSR1
SCHEMBL5390429 0.85 ALDH1A1 (1.00) LMNASMN1; SMN2MEN1KMT2ANPSR1
SCHEMBL17969765 0.84 MEN1 (0.79) LMNASMN1; SMN2MEN1KMT2ANPSR1
SCHEMBL8147516 0.82 LMNA (0.75) LMNASMN1; SMN2MEN1KMT2ANPSR1
SCHEMBL7099523 0.82 MEN1 (0.75) LMNASMN1; SMN2MEN1KMT2ANPSR1
SCHEMBL17969757 0.80 MEN1 (0.71) LMNASMN1; SMN2MEN1KMT2ANPSR1
SCHEMBL30885094 0.80 LMNA (0.88) LMNASMN1; SMN2MEN1KMT2ANPSR1
SCHEMBL17969760 0.78 NPSR1 (0.58) LMNASMN1; SMN2MEN1KMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9760029-B2 Electrophotographic photosensitive member, image forming apparatus, and process cartridge KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2017-09-12 — — US disclosed
US-9760029-B2 Electrophotographic photosensitive member, image forming apparatus, and process cartridge KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2017-09-12 — — US disclosed
US-20160223923-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2016-08-04 — — US disclosed
US-20160223923-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2016-08-04 — — US disclosed
EP-3051352-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER AND METHOD FOR MANUFACTURING THE SAME, AND IMAGE FORMING APPARATUS Kyocera Document Solutions Inc. (JP) 2016-08-03 — — EP disclosed
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