SCHEMBL17969760

SCHEMBL17969760

CCc1ccc(OC(=O)C2=C(c3ccccc3)C(=O)c3ccccc3C2=O)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 5/20 0.58
MEN1 O00255 4/20 0.58
LMNA P02545 4/20 0.58
KMT2A Q03164 4/20 0.58
ALDH1A1 P00352 4/20 0.58
MAPT P10636 4/20 0.58
HTT P42858 4/20 0.58
HSP90AA1 P07900 3/20 0.58
HKDC1 Q2TB90 3/20 0.58
SMN1; SMN2 Q16637 3/20 0.58
RAB9A P51151 3/20 0.58
KDM4E B2RXH2 3/20 0.58
TDP1 Q9NUW8 3/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
NPC1 O15118 2/20 0.58
MAPK1 P28482 2/20 0.58
MPI P34949 2/20 0.58
TP53 P04637 1/20 0.58
HSP90AB1 P08238 1/20 0.55
FGFR1 P11362 6/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12382276 0.87 HSP90AA1 (0.61) NPSR1MEN1LMNAKMT2AALDH1A1
SCHEMBL17969754 0.86 HSP90AA1 (0.57) NPSR1MEN1LMNAKMT2AALDH1A1
SCHEMBL8338003 0.86 HSP90AA1 (0.56) NPSR1MEN1LMNAKMT2AALDH1A1
SCHEMBL7099261 0.81 LMNA (0.73) NPSR1MEN1LMNAKMT2AALDH1A1
SCHEMBL17969781 0.79 ALDH1A1 (0.78) NPSR1MEN1LMNAKMT2AALDH1A1
SCHEMBL17969764 0.78 LMNA (0.73) NPSR1MEN1LMNAKMT2AALDH1A1
SCHEMBL8340214 0.78 MAPT (0.56) NPSR1MEN1LMNAKMT2AALDH1A1
SCHEMBL17969780 0.77 FGFR1 (0.88) NPSR1MEN1LMNAKMT2AALDH1A1
SCHEMBL17969761 0.77 LMNA (0.66) NPSR1MEN1LMNAKMT2AALDH1A1
SCHEMBL445362 0.75 ALDH1A1 (0.56) NPSR1MEN1LMNAKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9760029-B2 Electrophotographic photosensitive member, image forming apparatus, and process cartridge KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2017-09-12 US disclosed
US-9760029-B2 Electrophotographic photosensitive member, image forming apparatus, and process cartridge KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2017-09-12 US disclosed
US-20160223923-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2016-08-04 US disclosed
US-20160223923-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2016-08-04 US disclosed
EP-3051352-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER AND METHOD FOR MANUFACTURING THE SAME, AND IMAGE FORMING APPARATUS Kyocera Document Solutions Inc. (JP) 2016-08-03 EP disclosed