Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 3/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL7099159 | 1.00 | CA2 (0.38) | CA2CA1CES2CES1 | |
| Potassium Ion SCHEMBL7095514 | 1.00 | CA2 (0.38) | CA2CA1CES2CES1 | |
| Potassium Ion SCHEMBL29407602 | 1.00 | CA2 (0.38) | CA2CA1CES2CES1 | |
| Potassium Ion SCHEMBL7096230 | 1.00 | CA2 (0.38) | CA2CA1CES2CES1 | |
| Potassium Ion SCHEMBL7096242 | 1.00 | CA2 (0.38) | CA2CA1CES2CES1 | |
| Potassium Ion SCHEMBL7097763 | 1.00 | CA2 (0.38) | CA2CA1CES2CES1 | |
| Potassium Ion SCHEMBL1311260 | 1.00 | CA2 (0.38) | CA2CA1CES2CES1 | |
| Potassium Ion SCHEMBL1309924 | 1.00 | CA2 (0.38) | CA2CA1CES2CES1 | |
| Potassium Ion SCHEMBL7094806 | 1.00 | CA2 (0.38) | CA2CA1CES2CES1 | |
| Potassium Ion SCHEMBL7100047 | 1.00 | CA2 (0.38) | CA2CA1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0964036-B1 | Water-based ball-point pen ink composition | PILOT INK CO LTD (JP) | 2003-08-27 | — | — | EP | disclosed |
| US-6261352-B1 | BETAINE, SULFO ESTER | THE PILOT INK CO., LTD. (JP) | 2001-07-17 | — | — | US | disclosed |
| EP-0964036-A2 | Water-based ball-point pen ink composition | THE PILOT INK CO., LTD. (JP) | 1999-12-15 | — | — | EP | disclosed |