Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11070962 | 0.77 | KDM4E (0.44) | ROCK2MTNR1AMTNR1BKDM4EALDH1A1 | |
| SCHEMBL27580125 | 0.77 | MTNR1B (0.42) | ROCK2MTNR1AMTNR1BKDM4EALDH1A1 | |
| SCHEMBL7066589 | 0.74 | ICAM1 (0.41) | ROCK2MTNR1AMTNR1BKDM4EALDH1A1 | |
| SCHEMBL28160791 | 0.73 | ALDH1A1 (0.43) | ROCK2MTNR1AMTNR1BKDM4EALDH1A1 | |
| SCHEMBL7461216 | 0.72 | ADRA1A (0.50) | ROCK2MTNR1AMTNR1BKDM4EALDH1A1 | |
| SCHEMBL7065988 | 0.72 | PLA2G2A (0.43) | ROCK2MTNR1AMTNR1BKDM4EALDH1A1 | |
| SCHEMBL7100441 | 0.72 | MTNR1B (0.40) | ROCK2MTNR1AMTNR1BKDM4EALDH1A1 | |
| SCHEMBL2544860 | 0.71 | MTNR1A (0.61) | ROCK2MTNR1AMTNR1BKDM4EALDH1A1 | |
| SCHEMBL6269567 | 0.71 | KCNH2 (0.42) | ROCK2KDM4ELMNAHTR1AADRA1D | |
| SCHEMBL2533923 | 0.70 | KCNH2 (0.46) | ROCK2KDM4ELMNAHTR1AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337529-A2 | HETEROCYCLYLALKYL PIPERIDINE DERIVATIVES, THEIR PREPARATION AND COMPOSITIONS CONTAINING SAME | Aventis Pharma S.A. (FR) | 2003-08-27 | — | — | EP | disclosed |
| WO-2002040474-A2 | HETEROCYCLYLALKYL PIPERIDINE DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2002-05-23 | — | — | WO | disclosed |