Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.42 |
| ▸ | ITGAV | P06756 | 2/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7099303 | 0.92 | KDM4E (0.43) | ITGB3ITGAVKDM4ERECQLITGA2B | |
| SCHEMBL7104747 | 0.90 | CTSA (0.42) | ITGB3ITGAVKDM4ERECQLITGA2B | |
| SCHEMBL7104880 | 0.84 | ITGB3 (0.43) | ITGB3ITGAVKDM4ERECQLITGA2B | |
| SCHEMBL7105220 | 0.84 | ITGB3 (0.47) | ITGB3ITGAV | |
| SCHEMBL7100982 | 0.81 | ITGB3 (0.51) | ITGB3ITGAVITGA2BMEN1POLB | |
| SCHEMBL7103717 | 0.80 | ITGB3 (0.46) | ITGB3ITGAVKDM4EITGA2BMEN1 | |
| SCHEMBL7099306 | 0.74 | ITGB3 (0.51) | ITGB3ITGAVITGA2BMEN1KMT2A | |
| SCHEMBL7099318 | 0.71 | ITGB3 (0.42) | ITGB3ITGAVITGA2B | |
| SCHEMBL7104753 | 0.71 | ITGB3 (0.51) | ITGB3ITGAVITGA2BMEN1KMT2A | |
| SCHEMBL7099324 | 0.69 | ITGB3 (0.41) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6649613-B1 | Integrin inhibitors | MERCK PATENT GMBH (DE) | 2003-11-18 | — | — | US | disclosed |
| EP-1194401-B1 | DIACYLHYDRAZINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2003-09-10 | — | — | EP | disclosed |