SCHEMBL7101264

SCHEMBL7101264

Fc1ccccc1OCBr

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.52
TDP1 Q9NUW8 1/20 0.52
KDM4E B2RXH2 4/20 0.43
KMT2A Q03164 3/20 0.43
MEN1 O00255 2/20 0.43
CYP1A2 P05177 2/20 0.43
CYP2D6 P10635 2/20 0.43
CYP2C9 P11712 2/20 0.43
CYP2C19 P33261 2/20 0.43
ALDH1A1 P00352 2/20 0.43
RECQL P46063 1/20 0.43
CYP3A4 P08684 1/20 0.43
DAO P14920 1/20 0.42
HPGD P15428 1/20 0.42
MRGPRX4 Q96LA9 1/20 0.41
TP53 P04637 1/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
LMNA P02545 1/20 0.40
MAPK1 P28482 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31596115 0.82 L3MBTL1 (0.58) L3MBTL1TDP1KDM4EKMT2AMEN1
SCHEMBL10971184 0.82 SLC6A2 (0.43) L3MBTL1TDP1
SCHEMBL1728656 0.82 L3MBTL1 (0.58) L3MBTL1TDP1KDM4EKMT2AMEN1
SCHEMBL31319551 0.82 KDM4E (0.46) L3MBTL1TDP1KDM4EALDH1A1HPGD
SCHEMBL29824548 0.80 L3MBTL1 (0.61) L3MBTL1TDP1KDM4EKMT2AMEN1
SCHEMBL3074417 0.80 L3MBTL1 (0.61) L3MBTL1TDP1KDM4EKMT2AMEN1
SCHEMBL1282346 0.79 L3MBTL1 (0.65) L3MBTL1TDP1KDM4EKMT2AMEN1
SCHEMBL575077 0.78 L3MBTL1 (0.59) L3MBTL1TDP1KDM4EKMT2AMEN1
SCHEMBL3235716 0.77 L3MBTL1 (0.62) L3MBTL1TDP1KDM4EKMT2AMEN1
SCHEMBL15922778 0.77 L3MBTL1 (0.62) L3MBTL1TDP1KDM4EKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109524612-A Secondary battery 宁德时代新能源科技股份有限公司 2019-03-26 CN disclosed
CN-109467572-A 3, 5-diphosphazene p-phenylene diether additive and lithium ion battery electrolyte containing same 合肥国轩高科动力能源有限公司 2019-03-15 CN disclosed
EP-3060549-B1 NOVEL ANTIFUNGAL OXODIHYDROPYRIDINECARBOHYDRAZIDE DERIVATIVE DAE WOONG PHARMA (KR) 2019-02-13 EP disclosed
US-9617216-B2 Antifungal oxodihydropyridinecarbohydrazide derivative DAEWOONG PHARMACEUTICAL CO., LTD. (KR) 2017-04-11 US disclosed
US-20160304460-A1 NOVEL ANTIFUNGAL OXODIHYDROPYRIDINECARBOHYDRAZIDE DERIVATIVE DAEWOONG PHARMACEUTICAL CO., LTD. (KR) 2016-10-20 US disclosed
EP-3060549-A1 NOVEL ANTIFUNGAL OXODIHYDROPYRIDINECARBOHYDRAZIDE DERIVATIVE Daewoong Pharmaceutical Co., Ltd. (KR) 2016-08-31 EP disclosed
CN-105637064-A Fluorinated phenyl thiophene-based polymerizable mesogenic compound having improved solubility in host liquid crystal, method for producing same, and polymerizable liquid crystal composition containing same DONGJIN SEMICHEM CO LTD 2016-06-01 CN disclosed
CN-105008409-A Alpha-olefin polymer and method for producing hydrogenated alpha-olefin polymer IDEMITSU KOSAN CO 2015-10-28 CN disclosed
WO-2015060613-A1 NOVEL ANTIFUNGAL OXODIHYDROPYRIDINECARBOHYDRAZIDE DERIVATIVE DAEWOONG PHARMACEUTICAL CO., LTD. (KR) 2015-04-30 WO disclosed
CN-104185625-A Fused azole derivative TAISHO PHARMACEUTICAL CO LTD 2014-12-03 CN disclosed
CN-103965147-A Benzofuran derivatives TAKEDA PHARMACEUTICAL 2014-08-06 CN disclosed
CN-102421767-B Benzofuran derivatives TAKEDA PHARMACEUTICAL 2014-06-18 CN disclosed
US-20140107135-A1 PYRIMIDINONE INHIBITORS OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 AUSPEX PHARMACEUTICALS, INC. (US) 2014-04-17 US disclosed
WO-2003095441-A1 INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME PFIZER INC. (US) 2003-11-20 WO disclosed
US-5223536-A Pyrethroid-like pesticides FMC CORPORATION (US) 1993-06-29 US disclosed
WO-1993001715-A1 1,4-DIARYL-1-CYCLOPROPYL-4-SUBSTITUTED BUTANES AS INSECTICIDES AND ACARICIDES FMC CORPORATION (US) 1993-02-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160304460-A1 NOVEL ANTIFUNGAL OXODIHYDROPYRIDINECARBOHYDRAZIDE DERIVATIVE PITHD1, HPD, QDPR L3MBTL1 4594/4885TDP1 1802/4885KDM4E 841/4885
US-20140107135-A1 PYRIMIDINONE INHIBITORS OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 PLA2G1B, PLA2G4A, PLA2G4B L3MBTL1 3877/4885TDP1 784/4885KDM4E 3515/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.