SCHEMBL3074417

SCHEMBL3074417

Fc1ccccc1OCCCBr

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 5/20 0.61
TDP1 Q9NUW8 1/20 0.61
KDM4E B2RXH2 6/20 0.51
KMT2A Q03164 3/20 0.51
ALDH1A1 P00352 3/20 0.51
MEN1 O00255 2/20 0.51
CYP1A2 P05177 2/20 0.51
CYP2D6 P10635 2/20 0.51
CYP2C9 P11712 2/20 0.51
CYP2C19 P33261 2/20 0.51
RECQL P46063 1/20 0.51
CYP3A4 P08684 1/20 0.51
MAPK1 P28482 2/20 0.47
TTR P02766 1/20 0.47
MAPT P10636 1/20 0.44
RAB9A P51151 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
TP53 P04637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29824548 1.00 L3MBTL1 (0.61) L3MBTL1TDP1KDM4EKMT2AALDH1A1
SCHEMBL1282346 0.94 L3MBTL1 (0.65) L3MBTL1TDP1KDM4EKMT2AALDH1A1
SCHEMBL3235716 0.92 L3MBTL1 (0.62) L3MBTL1TDP1KDM4EKMT2AALDH1A1
SCHEMBL15922778 0.92 L3MBTL1 (0.62) L3MBTL1TDP1KDM4EKMT2AALDH1A1
SCHEMBL1728656 0.89 L3MBTL1 (0.58) L3MBTL1TDP1KDM4EKMT2AALDH1A1
SCHEMBL31596115 0.89 L3MBTL1 (0.58) L3MBTL1TDP1KDM4EKMT2AALDH1A1
SCHEMBL29755650 0.84 KDM4E (0.52) L3MBTL1TDP1KDM4EALDH1A1CYP1A2
SCHEMBL17911627 0.84 KDM4E (0.52) L3MBTL1TDP1KDM4EALDH1A1CYP1A2
SCHEMBL3066339 0.84 L3MBTL1 (0.44) L3MBTL1TDP1KDM4EKMT2AALDH1A1
SCHEMBL25235421 0.82 L3MBTL1 (0.43) L3MBTL1TDP1KDM4EKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117105872-A Benzodiazepine compound and preparation method and application thereof 徐州医科大学 2023-11-24 CN claimed
US-20160002220-A1 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS GLAXO GROUP LTD (GB) 2016-01-07 US claimed
US-20070185155-A1 Muscarinic acetylcholine receptor antagonists GLAXO GROUP LIMITED (GB) 2007-08-09 US claimed
US-12583818-B2 Compound, preparation method thereof, and use thereof DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION (KR) 2026-03-24 US disclosed
US-20250388581-A1 ORGANIC COMPOUNDS INTRA CELLULAR THERAPIES INC (US) 2025-12-25 US disclosed
US-12331052-B2 Organic compounds INTRA-CELLULAR THERAPIES, INC. (US) 2025-06-17 US disclosed
EP-4065553-B1 NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF DAEGU GYEONGBUK MEDICAL INNOVATION FOUND (KR) 2025-01-29 EP disclosed
CN-117105872-A Benzodiazepine compound and preparation method and application thereof 徐州医科大学 2023-11-24 CN disclosed
US-20230142654-A1 NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF PIMEDBIO, INC. (KR) 2023-05-11 US disclosed
US-20230142654-A1 NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF PIMEDBIO, INC. (KR) 2023-05-11 US disclosed
US-20230142654-A1 NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF PIMEDBIO, INC. (KR) 2023-05-11 US disclosed
EP-1740177-A2 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS GLAXO GROUP LIMITED (GB) 2007-01-10 EP disclosed
US-7135466-B2 Quinoline and quinazoline derivatives and drugs containing the same KIRIN BEER KABUSHIKI KAISHA (JP) 2006-11-14 US disclosed
US-20060211717-A1 Quinoline and quinazoline derivatives and drugs containing the same KIRIN BEER KABUSHIKI KAISHA (JP) 2006-09-21 US disclosed
EP-1670760-A1 ORGANIC COMPOUNDS Speedel Experimenta AG (CH) 2006-06-21 EP disclosed
WO-2005123748-A1 NOVEL OXABISPIDINE COMPOUNDS AND THEIR USE IN THE TREATMENT OF CARDIAC ARRHYTHMIAS ASTRAZENECA AB (SE) 2005-12-29 WO disclosed
WO-2005104745-A2 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS GLAXO GROUP LIMITED (GB) 2005-11-10 WO disclosed
WO-2005061457-A1 ORGANIC COMPOUNDS SPEEDEL EXPERIMENTA AG (CH) 2005-07-07 WO disclosed
US-20040132727-A1 Quinoline and quinazoline derivatives and drugs containing the same KIRIN HOLDINGS KABUSHIKI KAISHA (JP) 2004-07-08 US disclosed
EP-1243582-A1 QUINOLINE AND QUINAZOLINE DERIVATIVES AND DRUGS CONTAINING THE SAME KIRIN BEER KABUSHIKI KAISHA (JP) 2002-09-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12583818-B2 Compound, preparation method thereof, and use thereof TYRO3, TH, SRMS L3MBTL1 4000/4885TDP1 2386/4885KDM4E 2818/4885
US-20160002220-A1 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS CHRM3, CHRNG, CHRM2 L3MBTL1 2063/4885TDP1 3754/4885KDM4E 3920/4885
US-20250388581-A1 ORGANIC COMPOUNDS OPRD1, OPRM1, HTR2C L3MBTL1 1834/4885TDP1 2704/4885KDM4E 2885/4885
US-12331052-B2 Organic compounds OPRD1, OPRK1, OPRM1 L3MBTL1 3475/4885TDP1 3327/4885KDM4E 4577/4885
US-20060211717-A1 Quinoline and quinazoline derivatives and drugs containing the same PDGFRA, PDGFRB, PDGFA L3MBTL1 1545/4885TDP1 1586/4885KDM4E 1657/4885
US-20230142654-A1 NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF TYR, TYRO3, TH L3MBTL1 4786/4885TDP1 1643/4885KDM4E 619/4885
US-20040132727-A1 Quinoline and quinazoline derivatives and drugs containing the same PDGFRA, PDGFRB, PDGFA L3MBTL1 1895/4885TDP1 2348/4885KDM4E 1526/4885
US-20070185155-A1 Muscarinic acetylcholine receptor antagonists CHRM3, CHRNG, CHRM2 L3MBTL1 1742/4885TDP1 3416/4885KDM4E 3835/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.