Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 5/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7096838 | 0.80 | PDE4A (0.65) | BLMCYP3A4PMP22ALDH1A1GDA | |
| SCHEMBL8355196 | 0.79 | CYP3A4 (0.64) | BLMCYP3A4PMP22ALDH1A1LMNA | |
| SCHEMBL26925735 | 0.78 | CYP3A4 (0.66) | BLMCYP3A4PMP22ALDH1A1LMNA | |
| SCHEMBL11442354 | 0.74 | BLM (0.54) | BLMCYP3A4PMP22ALDH1A1LMNA | |
| SCHEMBL7100345 | 0.73 | ADORA2B (0.50) | BLMCYP3A4PMP22LMNATSHR | |
| SCHEMBL7403404 | 0.72 | ALDH1A1 (0.57) | BLMCYP3A4PMP22ALDH1A1LMNA | |
| SCHEMBL8061720 | 0.72 | LMNA (0.54) | BLMCYP3A4PMP22ALDH1A1LMNA | |
| SCHEMBL31065362 | 0.71 | CYP3A4 (0.52) | BLMCYP3A4PMP22ALDH1A1LMNA | |
| SCHEMBL7099928 | 0.71 | ADORA2B (0.50) | BLMCYP3A4PMP22PDE4AADORA2A | |
| SCHEMBL6344281 | 0.71 | LMNA (0.52) | BLMCYP3A4PMP22ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140952-B1 | ORGANO-PHOSPHORUS COMPOUNDS AND THEIR UTILIZATION | BIOAGENCY AG (DE) | 2003-09-03 | — | — | EP | disclosed |
| EP-1140952-A1 | ORGANO-PHOSPHORUS COMPOUNDS AND THEIR UTILIZATION | Jomaa Pharmaka GmbH (DE) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000037477-A1 | ORGANO-PHOSPHORUS COMPOUNDS AND THEIR UTILIZATION | JOMAA PHARMAKA GMBH (DE) | 2000-06-29 | — | — | WO | disclosed |